Membrane Transporter/Ion Channel
- Piezo Channels(1)
- Aquaporins(1)
- AMPAR(62)
- ATPase(83)
- Calcium Channel(316)
- Cannabinoid Transporters(6)
- CFTR(41)
- Chloride Channels(13)
- GABA Receptor(196)
- Gardos Channel(1)
- Glucose Transporters(9)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(19)
- GTPase(21)
- Kv1.3(1)
- ICB(3)
- Lipophilic platinum complex(1)
- M2 ion Channel(1)
- MCT2(4)
- Monoamine transporter(17)
- Monocarboxylate Transporters(12)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(18)
- NKCC(7)
- NMDA Receptor(83)
- Nucleoside Transporters(4)
- Pannexin-1(4)
- P2X purinergic receptor(73)
- P-gp(14)
- Proton Pump(55)
- Potassium Channel(283)
- Sodium Channel(189)
- TRP Channel(157)
- TRPV1(11)
- URAT1(8)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(12)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(25)
- CRAC Channel(14)
- EAAT2(6)
- HCN Channel(5)
- Na+/HCO3- Cotransporter(2)
- Na+/K+ ATPase(34)
- P-glycoprotein(57)
- iGluR(166)
- nAChR(99)
- VDAC(2)
- GlyR(1)
Products for Membrane Transporter/Ion Channel
- Cat.No. Product Name Information
- GC60750 Dehydrosoyasaponin I
- GC64863 Dendrotoxin K Dendrotoxin K is a Kv1.1 channel blocker.
- GC16354 Dequalinium Chloride anti-tumor agent and PKC inhibitor
- GC43412 Desacetyl Bisacodyl Desacetyl bisacodyl (DAB) is an active metabolite of two stimulant laxatives, bisacodyl and sodium picosulfate.
- GC49242 Descarbonyl Lacosamide A potential impurity found in commercial preparations of lacosamide
- GC12593 Desformylflustrabromine hydrochloride Positive allosteric modulator of nicotinic α4β2 receptors
- GC38903 Deslanoside A cardiac glycoside
- GC49866 Desmethyl Carvedilol An active metabolite of carvedilol
- GC49409 Desmethyl Ranolazine A metabolite of ranolazine
- GC49025 Desogestrel-13C2-d2 An internal standard for the quantification of desogestrel
- GC25345 Deudextromethorphan (AVP-786) Deudextromethorphan (AVP-786) is an active N-methyl-D-aspartate (NMDA) receptor antagonist.
- GC16622 Dexlansoprazole Dexlansoprazole is the R enantiomer of Lansoprazole, Lansoprazole (AG 1749) is an orally active proton pump inhibitor which prevents the stomach from producing acid.
- GC10786 DHBP dibromide ryanodine receptor blocker
- GC35858 Dianicline Dianicline is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of drugs that includes varenicline and cytisine for smoking cessation.
-
GC11598
Diazoxide
positive allosteric modulator of the AMPA and kainate receptors
- GC15915 Dibucaine Local anesthetic
- GC16696 Dibucaine (Cinchocaine) HCl Sodium channel inhibitor
- GC35860 Dibucaine hydrochloride
- GC43442 Dibutyryl-Cyclic GMP (sodium salt) Dibutyryl-Cyclic GMP (sodium salt) (Bt2cGMP sodium) is a cell-permeable cGMP analogue.
- GC34013 Digitoxin A cardiac glycoside with diverse biological activities
- GC13108 Digoxin Na+/K+ ATPase pump inhibitor
- GC38223 Dihydroberberine
- GC67924 Dihydrocapsiate
- GC10530 Dihydroergotoxine mesylate GABAA receptor modulator
-
GC14271
Dihydrokainic acid
EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
- GC15863 Dilazep dihydrochloride vasodilator that acts as an adenosine reuptake inhibitor
- GC43464 Diltiazem (hydrochloride) Diltiazem (hydrochloride) is an analytical reference standard that is functionally categorized as a calcium channel blocker.
- GC64299 Diltiazem-d3 hydrochloride
- GC66836 Dimethyl L-glutamate Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulate insulin release induced by Glucose. Dimethyl L-glutamate suppresses the KATP channel activities. Dimethyl L-glutamate inhibits E. gracilis growth and causes abnormal cell division. Dimethyl L-glutamate can be used in the research of diabetes, glucose transport, phosphorylation, and further metabolism.
- GC38484 Dimethyl lithospermate B Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist.
- GC32185 Dinotefuran (MTI-446) Dinotefuran (MTI-446) is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.
- GC49129 Diphenidol-d10 An internal standard for the quantification of diphenidol
-
GC12520
Diphenyleneiodonium chloride
Diphenyleneiodonium (DPI) chloride (DPIC), as a NADH/NADPH oxidase inhibitor, has possessing potent antimicrobial activity against Mtb and S. aureus.
- GC39734 Diphyllin Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM.
- GC64121 Dirocaftor
- GC43478 Disopyramide Disopyramide is a sodium channel blocker that, in rabbit ventricular myocytes, binds and dissociates from open channels more quickly than from resting channels.
- GC18503 DK-AH 269 Cilobradine is an HCN Channel blocker; an open channel blocker of neuronal Ih and related cardiac If channels.
- GC17206 DL-AP5 A NMDA antagonist
- GC14897 DL-AP5 Sodium salt NMDA receptor antagonist
- GC11335 DL-AP7 first generation phosphono NMDA antagonist
- GC63881 DL-Phenylalanine-d5 hydrochloride
- GC38472 DL-TBOA An EAAT inhibitor
- GC16670 DL-TBOA inhibitor of excitatory amino acid transporters
- GC13405 DMCM hydrochloride Benzodiazepine inverse agonist
- GC11429 DMP 543 K+ channel blocker and acetylcholine release stimulator
- GC32755 DNQX (FG 9041) DNQX (FG 9041) (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively).
-
GC10275
DNQX disodium salt
Selective non-NMDA receptor antagonist
- GC16627 Docosahexaenoyl Serotonin TRPV1 channel inhibitor
- GC35892 Dofequidar A quinoline derivative and inhibitor of multidrug resistance
- GC13375 Dofequidar fumarate MDR reversal agent
- GC17152 Dofetilide Potassium channel inhibitor
- GC47260 Dofetilide-d4 An internal standard for the quantification of dofetilide
- GC49056 Dolasetron-d4 An internal standard for the quantification of dolasetron
- GC10861 Domiphen Bromide Quaternary ammonium antiseptic
- GC32652 Dopropidil Dopropidil is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity andanti-ischemic effects in several predictive animal models.
- GC16537 Doxapram Respiratory stimulant
- GC13976 Doxapram HCl Potassium channel inhibitor
-
GC14150
DPNI-caged-GABA
activates GABAA receptor
- GC12575 DPO-1 Blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels
-
GC10085
DQP 1105
NMDA receptor antagonist
- GC64568 DRB18 DRB18 is a potent pan-class GLUT inhibitor. DRB18 alters energy-related metabolism in A549 cells by changing the abundance of metabolites in glucose-related pathways. DRB18 can eventually lead to G1/S phase arrest and increase oxidative stress and necrotic cell death. DRB18 has anti-tumor activity.
- GC12234 Dronedarone HCl Dronedarone HCl is a non-iodinated amiodarone derivative that inhibits Na+, K+ and Ca2+ currents.
- GC43575 DS16570511 DS16570511 is an inhibitor of the mitochondrial calcium uniporter.
- GC12008 DS2 Positive allosteric modulator of δ-subunit containing GABAA receptors
- GC35903 DSP-2230 DSP-2230 is a selective Nav1.7/Nav1.8 blocker.
- GC10395 Dynasore Dynasore, as a GTPase inhibitor, can rapidly and reversibly inhibit dynamin activity, which prevents endocytosis.
- GC14179 Dynole 34-2 Dynamin I inhibitor
- GC35917 Dynorphin A (1-10) TFA
- GC35918 Dynorphin A 1-10 Dynorphin A 1-10 an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor.
- GC13490 E-4031 antiarrhythmic agent blocking the ATP-sensitive potassium channel
- GC17661 E-4031 dihydrochloride KV11.1 (hERG) channels blocker
- GC64288 EAAT2 activator 1 EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2).
-
GC18142
Eact
TMEM16A (ANO1) calcium-activated chloride channel (CaCC) activator
- GC32580 Efonidipine (NZ-105) Efonidipine (NZ-105)(NZ-105) is a dual T-type and L-type calcium channel blocker (CCB).
- GC32573 Efonidipine hydrochloride (NZ-105 hydrochloride) Efonidipine Hcl (NZ-105) is a dual T-type and L-type calcium channel blocker (CCB).
- GC35963 Efonidipine hydrochloride monoethanolate Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a dual T-type and L-type calcium channel blocker (CCB).
- GC43588 EGA EGA is an inhibitor of endosomal trafficking.
- GC12772 Eicosapentaenoyl Serotonin TRPV1 channel inhibitor
- GC15893 EIPA EIPA inhibited TRPP3-mediated Ca2+-activated currents with IC50 values of 10.5 µM.
-
GC35970
EIPA hydrochloride
EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM.
- GC17215 Elacridar An inhibitor of MRP-1 and BCRP
- GC17163 Elacridar hydrochloride An inhibitor of MRP-1 and BCRP
- GC30063 Eleclazine hydrochloride (GS 6615 hydrochloride) Eleclazine (GS 6615) hydrochloride is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC50 value of <1 μM and approximately 14.2 μM, respectively.
- GC62950 Eliapixant Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM.
- GC15343 Eliprodil NMDA receptor antagonist
- GC18890 Emamectin B1a Emamectin B1a is a semi-synthetic derivative of avermectin B1a .
- GC35975 Emamectin Benzoate Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects.
- GC35982 EN6 An activator of autophagy
- GC31340 Encequidar (HM30181) Encequidar (HM30181) (HM30181; HM30181A) is a potent and selective inhibitor of P-glycoprotein.
- GC33185 Encequidar mesylate (HM30181 (mesylate)) Encequidar mesylate (HM30181 (mesylate)) (HM30181 mesylate; HM30181A mesylate) is a competitive and potent P-glycoprotein inhibitor.
- GC43604 Endosulfan I Endosulfan I is an organochlorine insecticide and a stereoisomer of endosulfan II.
- GC43605 Endosulfan II Endosulfan II is an organochlorine insecticide and a stereoisomer of endosulfan I.
- GC34574 Endovion Endovion (NS3728) is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker.
- GC12140 Endoxifen Endoxifen Z-isomer is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα).
- GC35991 Endoxifen Z-isomer hydrochloride Endoxifen Z-isomer hydrochloride is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα).
- GC63367 Enflurane
- GC64459 Englerin A Englerin A is a potent and selective activator of TRPC4 and TRPC5 channels, with EC50s of 11.2 and 7.6 nM, respectively. Englerin A can induce renal carcinoma cells death by elevated Ca2+ influx and Ca2+ cell overload.
- GC16924 Eniporide Na+/H+ exchange inhibitor
- GC35993 Eniporide hydrochloride Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na+/H+ exchange inhibitor.
- GC17693 Enniatin B ionophore with some capacity to facilitate import of K+ and Na+ across membranes