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Membrane Transporter/Ion Channel

Products for  Membrane Transporter/Ion Channel

  1. Cat.No. Product Name Information
  2. GC60750 Dehydrosoyasaponin I Dehydrosoyasaponin I  Chemical Structure
  3. GC64863 Dendrotoxin K Dendrotoxin K is a Kv1.1 channel blocker. Dendrotoxin K  Chemical Structure
  4. GC16354 Dequalinium Chloride anti-tumor agent and PKC inhibitor Dequalinium Chloride  Chemical Structure
  5. GC43412 Desacetyl Bisacodyl Desacetyl bisacodyl (DAB) is an active metabolite of two stimulant laxatives, bisacodyl and sodium picosulfate. Desacetyl Bisacodyl  Chemical Structure
  6. GC49242 Descarbonyl Lacosamide A potential impurity found in commercial preparations of lacosamide Descarbonyl Lacosamide  Chemical Structure
  7. GC12593 Desformylflustrabromine hydrochloride Positive allosteric modulator of nicotinic α4β2 receptors Desformylflustrabromine hydrochloride  Chemical Structure
  8. GC38903 Deslanoside A cardiac glycoside Deslanoside  Chemical Structure
  9. GC49866 Desmethyl Carvedilol An active metabolite of carvedilol Desmethyl Carvedilol  Chemical Structure
  10. GC49409 Desmethyl Ranolazine A metabolite of ranolazine Desmethyl Ranolazine  Chemical Structure
  11. GC49025 Desogestrel-13C2-d2 An internal standard for the quantification of desogestrel Desogestrel-13C2-d2  Chemical Structure
  12. GC25345 Deudextromethorphan (AVP-786) Deudextromethorphan (AVP-786) is an active N-methyl-D-aspartate (NMDA) receptor antagonist. Deudextromethorphan (AVP-786)  Chemical Structure
  13. GC16622 Dexlansoprazole Dexlansoprazole is the R enantiomer of Lansoprazole, Lansoprazole (AG 1749) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Dexlansoprazole  Chemical Structure
  14. GC10786 DHBP dibromide ryanodine receptor blocker DHBP dibromide  Chemical Structure
  15. GC35858 Dianicline Dianicline is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of drugs that includes varenicline and cytisine for smoking cessation. Dianicline  Chemical Structure
  16. GC11598 Diazoxide

    positive allosteric modulator of the AMPA and kainate receptors

    Diazoxide  Chemical Structure
  17. GC15915 Dibucaine Local anesthetic Dibucaine  Chemical Structure
  18. GC16696 Dibucaine (Cinchocaine) HCl Sodium channel inhibitor Dibucaine (Cinchocaine) HCl  Chemical Structure
  19. GC35860 Dibucaine hydrochloride Dibucaine hydrochloride  Chemical Structure
  20. GC43442 Dibutyryl-Cyclic GMP (sodium salt) Dibutyryl-Cyclic GMP (sodium salt) (Bt2cGMP sodium) is a cell-permeable cGMP analogue. Dibutyryl-Cyclic GMP (sodium salt)  Chemical Structure
  21. GC34013 Digitoxin A cardiac glycoside with diverse biological activities Digitoxin  Chemical Structure
  22. GC13108 Digoxin Na+/K+ ATPase pump inhibitor Digoxin  Chemical Structure
  23. GC38223 Dihydroberberine Dihydroberberine  Chemical Structure
  24. GC67924 Dihydrocapsiate Dihydrocapsiate  Chemical Structure
  25. GC10530 Dihydroergotoxine mesylate GABAA receptor modulator Dihydroergotoxine mesylate  Chemical Structure
  26. GC14271 Dihydrokainic acid

    EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake

    Dihydrokainic acid  Chemical Structure
  27. GC15863 Dilazep dihydrochloride vasodilator that acts as an adenosine reuptake inhibitor Dilazep dihydrochloride  Chemical Structure
  28. GC43464 Diltiazem (hydrochloride) Diltiazem (hydrochloride) is an analytical reference standard that is functionally categorized as a calcium channel blocker. Diltiazem (hydrochloride)  Chemical Structure
  29. GC64299 Diltiazem-d3 hydrochloride Diltiazem-d3 hydrochloride  Chemical Structure
  30. GC66836 Dimethyl L-glutamate Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulate insulin release induced by Glucose. Dimethyl L-glutamate suppresses the KATP channel activities. Dimethyl L-glutamate inhibits E. gracilis growth and causes abnormal cell division. Dimethyl L-glutamate can be used in the research of diabetes, glucose transport, phosphorylation, and further metabolism. Dimethyl L-glutamate  Chemical Structure
  31. GC38484 Dimethyl lithospermate B Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist. Dimethyl lithospermate B  Chemical Structure
  32. GC32185 Dinotefuran (MTI-446) Dinotefuran (MTI-446) is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors. Dinotefuran (MTI-446)  Chemical Structure
  33. GC49129 Diphenidol-d10 An internal standard for the quantification of diphenidol Diphenidol-d10  Chemical Structure
  34. GC12520 Diphenyleneiodonium chloride

    Diphenyleneiodonium (DPI) chloride (DPIC), as a NADH/NADPH oxidase inhibitor, has possessing potent antimicrobial activity against Mtb and S. aureus.

    Diphenyleneiodonium chloride  Chemical Structure
  35. GC39734 Diphyllin Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM. Diphyllin  Chemical Structure
  36. GC64121 Dirocaftor Dirocaftor  Chemical Structure
  37. GC43478 Disopyramide Disopyramide is a sodium channel blocker that, in rabbit ventricular myocytes, binds and dissociates from open channels more quickly than from resting channels. Disopyramide  Chemical Structure
  38. GC18503 DK-AH 269 Cilobradine is an HCN Channel blocker; an open channel blocker of neuronal Ih and related cardiac If channels. DK-AH 269  Chemical Structure
  39. GC17206 DL-AP5 A NMDA antagonist DL-AP5  Chemical Structure
  40. GC14897 DL-AP5 Sodium salt NMDA receptor antagonist DL-AP5 Sodium salt  Chemical Structure
  41. GC11335 DL-AP7 first generation phosphono NMDA antagonist DL-AP7  Chemical Structure
  42. GC63881 DL-Phenylalanine-d5 hydrochloride DL-Phenylalanine-d5 hydrochloride  Chemical Structure
  43. GC38472 DL-TBOA An EAAT inhibitor DL-TBOA  Chemical Structure
  44. GC16670 DL-TBOA inhibitor of excitatory amino acid transporters DL-TBOA  Chemical Structure
  45. GC13405 DMCM hydrochloride Benzodiazepine inverse agonist DMCM hydrochloride  Chemical Structure
  46. GC11429 DMP 543 K+ channel blocker and acetylcholine release stimulator DMP 543  Chemical Structure
  47. GC32755 DNQX (FG 9041) DNQX (FG 9041) (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively). DNQX (FG 9041)  Chemical Structure
  48. GC10275 DNQX disodium salt

    Selective non-NMDA receptor antagonist

    DNQX disodium salt  Chemical Structure
  49. GC16627 Docosahexaenoyl Serotonin TRPV1 channel inhibitor Docosahexaenoyl Serotonin  Chemical Structure
  50. GC35892 Dofequidar A quinoline derivative and inhibitor of multidrug resistance Dofequidar  Chemical Structure
  51. GC13375 Dofequidar fumarate MDR reversal agent Dofequidar fumarate  Chemical Structure
  52. GC17152 Dofetilide Potassium channel inhibitor Dofetilide  Chemical Structure
  53. GC47260 Dofetilide-d4 An internal standard for the quantification of dofetilide Dofetilide-d4  Chemical Structure
  54. GC49056 Dolasetron-d4 An internal standard for the quantification of dolasetron Dolasetron-d4  Chemical Structure
  55. GC10861 Domiphen Bromide Quaternary ammonium antiseptic Domiphen Bromide  Chemical Structure
  56. GC32652 Dopropidil Dopropidil is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity andanti-ischemic effects in several predictive animal models. Dopropidil  Chemical Structure
  57. GC16537 Doxapram Respiratory stimulant Doxapram  Chemical Structure
  58. GC13976 Doxapram HCl Potassium channel inhibitor Doxapram HCl  Chemical Structure
  59. GC14150 DPNI-caged-GABA

    activates GABAA receptor

    DPNI-caged-GABA  Chemical Structure
  60. GC12575 DPO-1 Blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels DPO-1  Chemical Structure
  61. GC10085 DQP 1105

    NMDA receptor antagonist

    DQP 1105  Chemical Structure
  62. GC64568 DRB18 DRB18 is a potent pan-class GLUT inhibitor. DRB18 alters energy-related metabolism in A549 cells by changing the abundance of metabolites in glucose-related pathways. DRB18 can eventually lead to G1/S phase arrest and increase oxidative stress and necrotic cell death. DRB18 has anti-tumor activity. DRB18  Chemical Structure
  63. GC12234 Dronedarone HCl Dronedarone HCl is a non-iodinated amiodarone derivative that inhibits Na+, K+ and Ca2+ currents. Dronedarone HCl  Chemical Structure
  64. GC43575 DS16570511 DS16570511 is an inhibitor of the mitochondrial calcium uniporter. DS16570511  Chemical Structure
  65. GC12008 DS2 Positive allosteric modulator of δ-subunit containing GABAA receptors DS2  Chemical Structure
  66. GC35903 DSP-2230 DSP-2230 is a selective Nav1.7/Nav1.8 blocker. DSP-2230  Chemical Structure
  67. GC10395 Dynasore Dynasore, as a GTPase inhibitor, can rapidly and reversibly inhibit dynamin activity, which prevents endocytosis. Dynasore  Chemical Structure
  68. GC14179 Dynole 34-2 Dynamin I inhibitor Dynole 34-2  Chemical Structure
  69. GC35917 Dynorphin A (1-10) TFA Dynorphin A (1-10) TFA  Chemical Structure
  70. GC35918 Dynorphin A 1-10 Dynorphin A 1-10 an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A 1-10  Chemical Structure
  71. GC13490 E-4031 antiarrhythmic agent blocking the ATP-sensitive potassium channel E-4031  Chemical Structure
  72. GC17661 E-4031 dihydrochloride KV11.1 (hERG) channels blocker E-4031 dihydrochloride  Chemical Structure
  73. GC64288 EAAT2 activator 1 EAAT2 activator 1 is the potent activator of excitatory amino acid transporter 2 (EAAT2). EAAT2 activator 1  Chemical Structure
  74. GC18142 Eact

    TMEM16A (ANO1) calcium-activated chloride channel (CaCC) activator

    Eact  Chemical Structure
  75. GC32580 Efonidipine (NZ-105) Efonidipine (NZ-105)(NZ-105) is a dual T-type and L-type calcium channel blocker (CCB). Efonidipine (NZ-105)  Chemical Structure
  76. GC32573 Efonidipine hydrochloride (NZ-105 hydrochloride) Efonidipine Hcl (NZ-105) is a dual T-type and L-type calcium channel blocker (CCB). Efonidipine hydrochloride (NZ-105 hydrochloride)  Chemical Structure
  77. GC35963 Efonidipine hydrochloride monoethanolate Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a dual T-type and L-type calcium channel blocker (CCB). Efonidipine hydrochloride monoethanolate  Chemical Structure
  78. GC43588 EGA EGA is an inhibitor of endosomal trafficking. EGA  Chemical Structure
  79. GC12772 Eicosapentaenoyl Serotonin TRPV1 channel inhibitor Eicosapentaenoyl Serotonin  Chemical Structure
  80. GC15893 EIPA EIPA inhibited TRPP3-mediated Ca2+-activated currents with IC50 values of 10.5 µM. EIPA  Chemical Structure
  81. GC35970 EIPA hydrochloride

    EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM.

    EIPA hydrochloride  Chemical Structure
  82. GC17215 Elacridar An inhibitor of MRP-1 and BCRP Elacridar  Chemical Structure
  83. GC17163 Elacridar hydrochloride An inhibitor of MRP-1 and BCRP Elacridar hydrochloride  Chemical Structure
  84. GC30063 Eleclazine hydrochloride (GS 6615 hydrochloride) Eleclazine (GS 6615) hydrochloride is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC50 value of <1 μM and approximately 14.2 μM, respectively. Eleclazine hydrochloride (GS 6615 hydrochloride)  Chemical Structure
  85. GC62950 Eliapixant Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant  Chemical Structure
  86. GC15343 Eliprodil NMDA receptor antagonist Eliprodil  Chemical Structure
  87. GC18890 Emamectin B1a Emamectin B1a is a semi-synthetic derivative of avermectin B1a . Emamectin B1a  Chemical Structure
  88. GC35975 Emamectin Benzoate Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate  Chemical Structure
  89. GC35982 EN6 An activator of autophagy EN6  Chemical Structure
  90. GC31340 Encequidar (HM30181) Encequidar (HM30181) (HM30181; HM30181A) is a potent and selective inhibitor of P-glycoprotein. Encequidar (HM30181)  Chemical Structure
  91. GC33185 Encequidar mesylate (HM30181 (mesylate)) Encequidar mesylate (HM30181 (mesylate)) (HM30181 mesylate; HM30181A mesylate) is a competitive and potent P-glycoprotein inhibitor. Encequidar mesylate (HM30181 (mesylate))  Chemical Structure
  92. GC43604 Endosulfan I Endosulfan I is an organochlorine insecticide and a stereoisomer of endosulfan II. Endosulfan I  Chemical Structure
  93. GC43605 Endosulfan II Endosulfan II is an organochlorine insecticide and a stereoisomer of endosulfan I. Endosulfan II  Chemical Structure
  94. GC34574 Endovion Endovion (NS3728) is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion  Chemical Structure
  95. GC12140 Endoxifen Endoxifen Z-isomer is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα). Endoxifen  Chemical Structure
  96. GC35991 Endoxifen Z-isomer hydrochloride Endoxifen Z-isomer hydrochloride is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα). Endoxifen Z-isomer hydrochloride  Chemical Structure
  97. GC63367 Enflurane Enflurane  Chemical Structure
  98. GC64459 Englerin A Englerin A is a potent and selective activator of TRPC4 and TRPC5 channels, with EC50s of 11.2 and 7.6 nM, respectively. Englerin A can induce renal carcinoma cells death by elevated Ca2+ influx and Ca2+ cell overload. Englerin A  Chemical Structure
  99. GC16924 Eniporide Na+/H+ exchange inhibitor Eniporide  Chemical Structure
  100. GC35993 Eniporide hydrochloride Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na+/H+ exchange inhibitor. Eniporide hydrochloride  Chemical Structure
  101. GC17693 Enniatin B ionophore with some capacity to facilitate import of K+ and Na+ across membranes Enniatin B  Chemical Structure

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