GPCR/G protein
- Neuropeptide FF/AF Receptors(43)
- Neuropeptide S Receptor(1)
- GPBA Receptor(1)
- Trace Amine 1 Receptor(2)
- GPCR protein(1)
- FFAR3(1)
- Formyl Peptide Receptors(11)
- 5-HT Receptor(380)
- Acetylcholine(19)
- Adenosine Deaminase(10)
- Adenosine Receptor(123)
- Adenosine Kinase(4)
- Adiponectin Receptor(3)
- Adrenergic Receptor(389)
- Adrenergic Transporters(5)
- Apelin Receptor(9)
- Angiotensin Receptor(105)
- Bombesin Receptors(22)
- Bradykinin Receptors(27)
- Calcitonin and Related Receptors(10)
- Cannabinoid Receptor(128)
- Calcimimetic Agent(2)
- CaSR(20)
- CCK1 Receptors(7)
- CCK2 Receptors(7)
- CCR(73)
- Chemokine Receptors(25)
- CRF1 Receptors(9)
- CRF2 Receptors(3)
- CXCR(73)
- CysLT1 receptor(1)
- Endothelin Receptor(46)
- EP1 Receptor(2)
- EP4 Receptor(2)
- ERRγ(1)
- ETA Receptors(5)
- ETB Receptors(5)
- Free Fatty Acid Receptors(18)
- Galanin Receptors(11)
- Ghrelin Receptors(12)
- GHSR(18)
- GIP Receptor(5)
- Glucagon Receptor(61)
- Glucocorticoid Receptor(85)
- GLUT1(1)
- Gonadotropin-Releasing Hormone Receptors(3)
- GPCR19(12)
- GPR109A(3)
- GPR119(10)
- GPR120(9)
- GPR35(8)
- GPR44(1)
- GPR55(10)
- Hydroxycarboxylic Acid Receptors(5)
- Leukotriene Receptor(55)
- LPA Receptor(12)
- LPL Receptor(57)
- LTD4 Receptor(1)
- mGluR (109)
- Melanin-concentrating Hormone Receptors(7)
- Melanocortin (MC) Receptors(49)
- Melatonin Receptors(23)
- Motilin Receptor(7)
- MT Receptor(1)
- Non-selective CRF(7)
- Neurotensin Receptors(21)
- NK2 Receptors(7)
- NK3 Receptor(5)
- NOP Receptor(21)
- NPY Receptors(28)
- Orexin(3)
- Orphan 7-TM Receptors(6)
- OX Receptor(39)
- Oxytocin Receptors(21)
- P2Y Receptor(55)
- PACAP Receptors(3)
- PAF Receptors(8)
- Peptide Receptors(15)
- PGD2 Receptor(1)
- Prostaglandin Receptor(163)
- Prostanoid Receptors(25)
- Protease-Activated Receptors(10)
- RGS(2)
- S1P receptor(8)
- Secretin Receptors(1)
- Sensory Neuron-Specific Receptors(1)
- Somatostatin Receptor(33)
- Sigma Receptor(54)
- Vasopressin Receptor(31)
- 17,20-lyase(5)
- Ras(115)
- Urotensin-II Receptor(11)
- VIP Receptors(7)
- EBI2/GPR183(5)
- TSH Receptor(10)
- NK Receptor(1)
- GPR81(1)
- C3aR(1)
- CysLT2 receptor(1)
- S1P receptor inhibitor(22)
- CCKB(1)
- FFAR1 (GPR40)(20)
- GPR84(5)
- Neuromedin U Receptors(2)
- Kisspeptin Receptor(4)
- CRFR(21)
- RGS Protein(5)
- Urotensin Receptor(6)
- Cholecystokinin Receptor(23)
- GPR139(3)
- mAChR(172)
- MCHR1 (GPR24)(16)
- Neurokinin Receptor(70)
- cGMP(18)
- GRK(1)
Products for GPCR/G protein
- Cat.No. Product Name Information
- GC68435 Clazosentan
- GC12778 Clenbuterol (hydrochloride) sympathomimetic β2-adrenoceptor agonist used as a bronchodilator in the treatment of pulmonary diseases
- GC68418 Clenbuterol-d9
- GC62900 Clenproperol-D7 Clenproperol-D7 is the deuterium labeled Clenproperol.
- GC31048 Clidinium bromide (Ro 2-3773) Clidinium bromide (Ro 2-3773) is a quaternary amine antimuscarinic agent.
- GC11976 Clobetasol propionate Glucocorticoid receptor agonist
- GC39362 Clobetasone butyrate Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin.
- GC31037 Clocapramine (Clocarpramine)
- GC15107 Clomipramine HCl Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM.
- GC60717 Clonidine Clonidine is an alpha 2-adrenergic agonist.
- GC14032 Clonidine HCl Clonidine HCl is an agonist of α2-adrenoceptor and potent antihypertensive agent.
- GC35710 Clopidogrel Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor.
- GC15964 Clopidogrel hydrogen sulfate P2Y12 receptor antagonist
- GC35711 Clopidogrel thiolactone Clopidogrel thiolactone is an active metabolites containing thiols resulting from thionolactone transformation of clopidogrel.
- GC12949 Clorprenaline HCL Clorprenaline HCL is a β2-adrenergic receptor agonist that is implicated in bronchial expansion.
- GC17760 Clozapine Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia.
- GC50193 Clozapine - d8 Clozapine - d8 (HF 1854-d8) is the deuterium labeled Clozapine.
-
GC10822
Clozapine N-oxide (CNO)
A metabolite of clozapine and muscarinic DREADD agonist
- GC63801 CM398 CM398 is a highly selective, orally active sigma-2 receptor ligand (Ki=0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold).
- GC62347 CMC2.24 CMC2.24 (TRB-N0224), an orally active tricarbonylmethane agent, is effective against pancreatic tumor in mice by inhibiting Ras activation and its downstream effector ERK1/2 pathway.
- GC12627 Conivaptan HCl Conivaptan (hydrochloride) is a non-peptide antagonist of vasopressin receptor, with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively.
- GC18110 COR 170 inverse agonist of CB2 receptors
- GC50455 Cortagine Potent and selective CRF1 agonist
- GC12327 Corticosterone Corticosterone (17 deoxycortisol) is a glucocorticoid with oral activity and produced by adrenal cortex, which plays an important role in regulating the neuronal function of limbic system (including hippocampus, prefrontal cortex and amygdala).
- GC60724 Corticotropin-releasing factor (human) (acetate) Corticotropin-releasing factor human acetate (Human CRF acetate) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.
- GC33839 Cortisone (17-Hydroxy-11-dehydrocorticosterone)
- GC16772 Cortisone acetate Glucocorticoid receptor agonist
- GC12835 Cortistatin 14 Cortistatin 14 (CST-14, human, rat), a neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus.
- GC35730 Cortistatin-14 TFA Cortistatin-14 (TFA), a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5).
- GC10777 Cortistatin-8 ghrelin receptor antagonist
- GC39363 Cortodoxone Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).
- GC64090 Corydalmine Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi.
- GC39364 Cotadutide acetate Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively.
- GC47122 Coumaphos An organophosphate pesticide
- GC50042 CP 122721 hydrochloride High affinity NK1 antagonist
- GC11802 CP 135807 5-HT1D receptor agonist
- GC12170 CP 154526 CRF1 receptor antagonist
-
GC31043
CP 316311
CP 316311 is a potent and selective CRF1 receptor antagonist with an IC50 value of 6.8 nM.
- GC30863 CP 376395 (CP-316311) CP 376395 (CP-316311) is a potent and selective Corticotropin releasing factor 1 (CRF1) receptor antagonist.
- GC10548 CP 376395 hydrochloride CRF1 receptor antagonist
- GC10068 CP 93129 dihydrochloride 5-HT1B agonist, potent and highly selective
- GC16653 CP 94253 hydrochloride 5-HT1B agonist
- GC32015 CP-105696 (Pfizer 105696) CP-105696 (Pfizer 105696) is a potent and selective Leukotriene B4 Receptor antagonist, with an IC50 of 8.42 nM.
- GC17205 CP-945598 HCl CP-945598 HCl is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor.
- GC31923 CP-96486 CP-96486 is a potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Kis of 20 and 24 nM, respectively.
- GC32734 CPI-444 (V81444) CPI-444 (V81444) (V81444) is a potent, orally active and selective adenosine A2A receptor (A2AR) antagonist, which induces antitumor responses.
- GC13426 CPPHA A positive allosteric modulator of the mGluR5
- GC14137 CRF (6-33) CRF (6-33) is a CRF binding protein (CRF-BP) ligand inhibitor.
- GC15737 CRF (human, rat) Corticotropin-releasing factor human (Human CRF) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.
- GC35748 CRF, bovine CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.
- GC34542 CRF, bovine TFA CRF, bovine (TFA) is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.
- GC18099 CRSP-1 Endogenous central calcitonin (CT) receptor agonist
- GC31903 CRTh2 antagonist 1 CRTh2 antagonist 1 is a CRTh2 antagonist with an IC50 of 89 nM.
- GC31998 CRTH2-IN-1 (Ramatroban analog) CRTH2-IN-1 (Ramatroban analog) (Ramatroban analog) is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist with an IC50 of 6 nM in a human DP2 binding assay.
- GC13966 CS 2100 S1P1 agonist
- GC35751 CS-003 Free base CS-003 Free base (CS-003), a triple tachykinin receptor antagonist, shows high affinities for human (Neurokinin) NK1, NK2 and NK3 receptors with Ki values of 2.3 nM, 0.54 nM and 0.74 nM, respectively.
- GC65450 CT1812 CT1812 (Sigma-2 receptor antagonist 1) is a sigma-2 (σ-2) receptor antagonist.
- GC13360 CTCE 9908 CXCR4 antagonist
- GC16619 CTEP (RO4956371) CTEP (RO4956371) (RO 4956371) is a novel, long-acting, orally bioavailable allosteric antagonist ofmGlu5receptor withIC50of 2.2 nM, and shows > 1000-fold selectivity over other mGlu receptors.
-
GC68909
Cudarolimab
Cudarolimab (IBI101) is a fully human anti-OX40 (CD134, a co-stimulatory molecule expressed by activated immune cells) antibody. Cudarolimab inhibits the binding of OX40 to its ligand OX40L. Cudarolimab has anti-tumor activity and can be used in cancer-related research.
- GC33697 Cutamesine (SA4503) Cutamesine (SA4503) (SA4503; AGY-94806) is a selective sigma 1 receptor(σ1R) agonist; high affinity for the sigma 1 receptor subtype labeled by (+)-[3H]pentazocine (IC50= 17.4±1.9 nM); 100-fold less affinity for the sigma 2 receptor.
- GC14706 CV 1808 Adenosine A2 receptor agonist
- GC65908 CXCR2 antagonist 2 CXCR2 antagonist 2 is a potent CXCR2 antagonist for cancer immunotherapy with an IC50 value of 95 nM.
- GC31754 CXCR2-IN-1 CXCR2-IN-1 is a central nervous system penetrant CXCR2 antagonist with a pIC50 of 9.3.
- GC62475 CXCR2-IN-2 CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist (IC50=5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively).
-
GC63411
CXCR7 antagonist-1
CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7.
- GC65476 CXCR7 antagonist-1 hydrochloride CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7.
- GC35763 CXCR7 modulator 1 CXCR7 modulator 1 (compound 25) is a potent and orally bioavailable peptoid hybrid CXCR7 modulator, with a Ki of 9 nM.
- GC34339 CXCR7 modulator 2 CXCR7 modulator 2 is a modulator of C-X-C Chemokine Receptor Type 7 (CXCR7), with a Ki of 13 nM.
- GC38760 Cyamemazine Cyamemazine is a neuroleptic agent that contains the phenothiazine chromophore.
-
GC43341
Cyclic GMP
Guanosine 3',5'-cyclic monophosphate (cyclic GMP or cGMP) is a second messenger that is biosynthesized from GTP by guanylate cyclases.
- GC10743 Cyclobenzaprine HCl Cyclobenzaprine HCl (MK130 hydrochloride) is a skeletal muscle relaxant and a central nervous system (CNS) depressant.
- GC31209 Cyclodrine hydrochloride Cyclodrine hydrochloride is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.
- GC43347 Cyclopentolate (hydrochloride) Cyclopentolate is an antagonist of muscarinic acetylcholine receptors (Kis = 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively).
- GC15495 Cyclosomatostatin somatostatin receptor antagonist
-
GC15319
Cyclosporin H
Selective and competitive formyl peptide receptor antagonist
- GC10728 CYM 50260 S1P4 agonist
- GC15903 CYM 50308 S1P4 agonist
- GC14350 CYM 50358 hydrochloride S1P4 antagonist
- GC18138 CYM 50769 neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist
- GC16567 CYM 5442 hydrochloride S1P1 agonist, potent and selective
-
GC15765
CYM 5520
noncompetitive allosteric agonist of S1P2
- GC16946 CYM 5541 sphingosine-1-phosphate receptor 3 (S1P3) allosteric agonist
- GC17307 CYM 9484 neuropeptide Y (NPY) Y2 receptor antagonist
- GC63345 CYM50358 CYM50358 is a potent and selective S1PR4 antagonist, with an IC50 of 25 nM.
- GC14747 CYN 154806 somatostatin sst2 receptor antagonist
- GC35787 CYN 154806 TFA CYN 154806 TFA, a cyclic octapeptide, is a potent and selective somatostatin sst2 receptor antagonist, with pIC50 values of 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively.
- GC65565 Cyproheptadine Cyproheptadine is a potent and orally active 5-HT2A receptor antagonist, with antidepressant and antiserotonergic effects.
- GC43353 Cyproheptadine (hydrochloride hydrate) Cyproheptadine (hydrochloride hydrate) is an antihistamine and is an antagonist of serotonin and histamine2.
- GC10698 Cyproheptadine hydrochloride serotonin and histamine antagonist as well as antimuscarinic reagent
- GC30665 D2343 D2343 is a β2-adrenoceptor agonist and also is an α1- adrenoceptor inhibitor.
- GC60737 D3-βArr
- GC38762 Dabuzalgron Dabuzalgron (Ro 115-1240) is an orally active and selective α-1A adrenergic receptor agonist for the treatment of urinary incontinence.
- GC31844 Dagrocorat (PF-00251802) Dagrocorat (PF-00251802) (PF-00251802) is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor.
- GC63872 Dagrocorat hydrochloride Dagrocorat (PF-00251802) hydrochloride is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor.
- GC38763 Daltroban Daltroban (BM-13505) is a selective and specific thromboxane A2 (TXA2) receptor antagonist.
- GC65550 Danavorexton Danavorexton is an orexin receptor agonist.
- GC19116 Danirixin Danirixin is a selective, and reversible CXCR2 antagonist, with IC50 of 12.5 nM for CXCL8.
- GC30188 Dapiprazole hydrochloride An α-adrenergic receptor antagonist
- GC17061 Dapoxetine HCl Selective serotonin reuptake inhibitor