GPCR/G protein
- Neuropeptide FF/AF Receptors(43)
- Neuropeptide S Receptor(1)
- GPBA Receptor(1)
- Trace Amine 1 Receptor(2)
- GPCR protein(1)
- FFAR3(1)
- Formyl Peptide Receptors(11)
- 5-HT Receptor(415)
- Acetylcholine(19)
- Adenosine Deaminase(12)
- Adenosine Receptor(133)
- Adenosine Kinase(5)
- Adiponectin Receptor(4)
- Adrenergic Receptor(404)
- Adrenergic Transporters(5)
- Apelin Receptor(9)
- Angiotensin Receptor(110)
- Bombesin Receptors(22)
- Bradykinin Receptors(27)
- Calcitonin and Related Receptors(10)
- Cannabinoid Receptor(137)
- Calcimimetic Agent(3)
- CaSR(24)
- CCK1 Receptors(7)
- CCK2 Receptors(7)
- CCR(79)
- Chemokine Receptors(25)
- CRF1 Receptors(9)
- CRF2 Receptors(3)
- CXCR(82)
- CysLT1 receptor(1)
- Endothelin Receptor(50)
- EP1 Receptor(3)
- EP4 Receptor(5)
- ERRγ(2)
- ETA Receptors(5)
- ETB Receptors(5)
- Free Fatty Acid Receptors(20)
- Galanin Receptors(11)
- Ghrelin Receptors(12)
- GHSR(22)
- GIP Receptor(5)
- Glucagon Receptor(66)
- Glucocorticoid Receptor(87)
- GLUT1(2)
- Gonadotropin-Releasing Hormone Receptors(3)
- GPCR19(13)
- GPR109A(4)
- GPR119(11)
- GPR120(12)
- GPR35(8)
- GPR44(1)
- GPR55(10)
- Hydroxycarboxylic Acid Receptors(5)
- Leukotriene Receptor(55)
- LPA Receptor(15)
- LPL Receptor(60)
- LTD4 Receptor(2)
- mGluR (115)
- Melanin-concentrating Hormone Receptors(7)
- Melanocortin (MC) Receptors(49)
- Melatonin Receptors(23)
- Motilin Receptor(7)
- MT Receptor(1)
- Non-selective CRF(7)
- Neurotensin Receptors(21)
- NK2 Receptors(7)
- NK3 Receptor(8)
- NOP Receptor(22)
- NPY Receptors(28)
- Orexin(3)
- Orphan 7-TM Receptors(6)
- OX Receptor(42)
- Oxytocin Receptors(21)
- P2Y Receptor(55)
- PACAP Receptors(3)
- PAF Receptors(8)
- Peptide Receptors(15)
- PGD2 Receptor(2)
- Prostaglandin Receptor(168)
- Prostanoid Receptors(25)
- Protease-Activated Receptors(10)
- RGS(4)
- S1P receptor(9)
- Secretin Receptors(1)
- Sensory Neuron-Specific Receptors(1)
- Somatostatin Receptor(34)
- Sigma Receptor(54)
- Vasopressin Receptor(33)
- 17,20-lyase(7)
- Ras(118)
- Urotensin-II Receptor(11)
- VIP Receptors(7)
- EBI2/GPR183(5)
- TSH Receptor(10)
- NK Receptor(1)
- GPR81(1)
- C3aR(1)
- CysLT2 receptor(1)
- S1P receptor inhibitor(22)
- CCKB(1)
- FFAR1 (GPR40)(22)
- GPR84(5)
- Neuromedin U Receptors(2)
- Kisspeptin Receptor(4)
- CRFR(21)
- RGS Protein(7)
- Urotensin Receptor(6)
- Cholecystokinin Receptor(23)
- GPR139(3)
- mAChR(179)
- MCHR1 (GPR24)(16)
- Neurokinin Receptor(72)
- cGMP(18)
- GRK(1)
Products for GPCR/G protein
- Cat.No. Product Name Information
- GC31974 A2B receptor antagonist 1 A2B receptor antagonist 1 is a potent A2B adenosine receptor antagonist extracted from patent WO 2009157938 A1 EXAMPLE 9B.
- GC62820 A2B receptor antagonist 2 A2B receptor antagonist 2 (compound 18) is an adenosine receptor A2B antagonist, with Ki values of 2.30 μM, 6.8 μM and 3.44 μM for rA1, rA2A and hA2B, respectively.
- GC32674 A81988 (Abbott81988) A81988 (Abbott81988) is a potent, competitive, non-peptidic antagonist of angiotensin AT1 receptors.
- GC41327 Aaptamine Aaptamine is a marine sponge alkaloid originally isolated from A.
- GC30993 AB-MECA AB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recombinant A1 and A3 receptors.
- GC67702 Abanoquil
- GC31055 Abaperidone Abaperidone is a potent antagonist of 5-HT2A?receptor and dopamine D2 receptor with IC50s of 6.2 and 17 nM.
- GC64356 Ablukast Ablukast (Ro 23-3544) is a specific and active leukotriene receptor antagonist.
- GC12728 Abn-CBD GPR55 cannabinoid receptor agonist
- GC50125 ABP 688 High affinity human mGlu5 antagonist
- GC13416 ABT 702 dihydrochloride Adenosine kinase inhibitor
- GC50695 ABT 702 hydrochloride
- GC10097 AC 187 Amylin receptor antagonist, Potent and selective
- GC50365 AC 265347 Biased allosteric modulator of calcium-sensing receptor (CaSR)
- GC10014 Ac-RYYRIK-NH2 High affinity ligand for the NOP site
- GC15444 Ac-RYYRWK-NH2 selective partial agonist peptide for the NOP receptor
- GC30859 AC260584 AC260584 is an M1 muscarinic receptor allosteric agonist with a pEC50 of 7.6.
- GC15522 Ac9-25 formyl peptide receptor 1 (FPR1) ligand
- GC60552 Acebutolol D7 Acebutolol D7 is a deuterium labeled Acebutolol.
- GC13000 Acebutolol HCl Acebutolol HCl is an orally active β1 adrenergic receptor (β1AR) antagonist.
- GC64332 Aceclidine Aceclidine is a modulator of M3 muscarinic acetylcholine receptor.
- GC34143 Acefylline (Theophyllineacetic acid) Acefylline (Theophyllineacetic acid) (Theophyllineacetic acid), a xanthine derivative, is an adenosine receptor antagonist. Acefylline (Theophyllineacetic acid) is a peptidylarginine deiminase (PAD) activator. Acefylline (Theophyllineacetic acid) is also a bronchodilator, which inhibits rat lung cAMP phosphodiesterase isoenzymes.
- GC62825 ACH-000143 ACH-000143 is a potent and orally active melatonin receptor agonist, with EC50 values of 0.06 nM and 0.32 nM for MT1 and MT2, respectively.
- GC15791 Acifran HM74A/GPR109A and GPR109B agonist,hypolipidemic agent
- GC14096 Aclidinium Bromide LAMAs antagonist
- GC14036 ACPT-II metabotropic receptor antagonist
- GC10623 ACS 67 analog of latanoprost (free acid),prostaglandin (PG) analog
- GC16336 ACT 335827 Orexin receptor 1 antagonist,potent and selective
- GC50142 ACT 462206 Potent, dual orexin receptor antagonist
- GC13236 ACT-132577 ACT-132577 (ACT-132577) is the major and pharmacologically active metabolite of Macitentan.
- GC35243 ACTH (1-14) TFA
- GC35244 ACTH (1-17) TFA
- GC12239 ACTH (1-39) ACTH (1-39) is a melanocortin receptor agonist.
- GC66383 ACTH (11-24) (acetate) ACTH (11-24) (acetate) is an adrenocorticotropic hormone (ACTH) receptor antagonist. ACTH (11-24) is a fragment of adrenocorticotropic and induces cortisol release. ACTH (11-24) can be used for the research of central nervous system.
- GC30547 ACTH 1-14 (Adrenocorticotropic Hormone Fragment 1-14) ACTH 1-14 (Adrenocorticotropic Hormone Fragment 1-14) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production.
- GC31109 ACTH 1-17 (α1-17-ACTH) ACTH 1-17 (α1-17-ACTH), an adrenocorticotropin analogue, is a potent human melanocortin 1 (MC1) receptor agonist with a Ki of 0.21 nM.
- GC31954 ACTH 11-24 (Adrenocorticotropic Hormone (11-24)) ACTH 11-24 (Adrenocorticotropic Hormone (11-24)) is an adrenocorticotropic hormone (ACTH) receptor antagonist.
- GC19630 Adenosine 2′-monophosphate Adenosine 2′-monophosphate (2'-AMP) is converted by extracellular 2',3'-CAMP.
- GC35248 Adenosine 5'-monophosphate monohydrate Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist.
- GC38733 Adenosine A1 receptor activator T62 Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor.
- GC38884 Adenosine amine congener An adenosine A1 receptor agonist
- GC35249 Adenosine antagonist-1 Adenosine antagonist-1 is an adenosine A3 receptor (AA3R) antagonist.
-
GC35250
Adenosine deaminase
Involved in metabolism of purines
- GC16930 Adenosine Kinase Inhibitor (hydrate) inhibitor of adenosine kinase
- GC65901 Adenosine receptor antagonist 2 Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC50s of 1 nM and 3 nM, respectively. Adenosine receptor antagonist 2 has anti-tumor activity.
- GC66007 Adenosine receptor antagonist 3 Adenosine receptor antagonist 3 is a potent antagonist of adenosine receptor. Adenosine receptor antagonist 3 has the potential for the research of cancer disease (extracted from patent WO2019233994A1, compound 1).
- GC10254 AdipoRon AdipoR1 and AdipoR2 agonist, first orally active
- GC35251 AdipoRon hydrochloride AdipoRon hydrochloride is an orally active and specific AdipoR agonist, binding to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM, respectively.
- GC31322 Adomeglivant (LY2409021) Adomeglivant (LY2409021) (LY2409021) is a potent, selective glucagon receptor (GluR) allosteric antagonist.
- GC35252 Adoprazine Adoprazine (SLV313) is a full 5-HT1A receptor agonist with a pEC50 of 9 at cloned h5-HT1A receptors.
- GC13814 Adrenalone HCl Decoyinine (Angustmycin A), a specific inhibitor of bacterial GMPS, has been isolated from Streptomyces .
- GC35254 Adrenocorticotropic Hormone (ACTH) (1-39), rat Adrenocorticotropic Hormone (ACTH) (1-39), rat is a potent melanocortin 2 (MC2) receptor agonist.
- GC35255 Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA Adrenocorticotropic Hormone (ACTH) (1-39), rat (TFA) is a potent melanocortin 2 (MC2) receptor agonist.
- GC10494 ADX-47273 mGluR5 receptor positive allosteric modulator, potent and selective
- GC30793 ADX88178 ADX88178 is a potent metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4.
- GC10219 AF-DX 116 AF-DX 116 (AF-DX 116) is a selective and competitive M2 muscarinic acetylcholine receptor antagonist, with IC50 values of 640 nM and 386 nM for rabbit peripheral lung and rat heart, respectively.
- GC19023 AF38469 AF38469 is a novel, selective, orally bioavailable Sortilin inhibitor with an IC50 value of 330 nM.
- GC38586 AF40431 AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 ?M and a Kd of 0.7 ?M .
- GC15147 AG 045572 GnRH antagonist
- GC11603 AG-041R gastrin/cholecystokinin-2 (CCKB) receptor antagonist
- GC30572 Aganepag (AGN 210937) Aganepag (AGN 210937) is a potent Prostanoid EP2 receptor agonist, with an EC50 of 0.19 nM, and shows no activity at EP4 receptor.
- GC64435 Aganepag isopropyl Aganepag isopropyl (AGN-210961) is an EP2 agonist.
- GC64665 AGI-41998 AGI-41998 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A).
- GC64635 AGI-43192 AGI-43192 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A).
- GC16831 Agmatine sulfate α2-adrenergic receptor ligand
- GC32599 AGN 192836 AGN 192836 is a potent and selective α2 adrenergic agonist with EC50s of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively.
- GC31972 AGN 210676 (Simenepag) AGN 210676 (Simenepag) is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM.
- GC40750 Agnuside Agnuside is an iridoid glycoside originally isolated from V.
- GC17981 Agomelatine MT1/MT2 / 5-HT2C agonist
- GC35269 Agomelatine hydrochloride Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively.
- GC35270 Agomelatine L(+)-Tartaric acid Agomelatine L(+)-Tartaric acid (S-20098 L(+)-Tartaric acid) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively.
- GC10197 AH 11110 hydrochloride α1B-AR ligand,subtype-selective
- GC17224 AH 23848 (calcium salt) dual antagonist of TP1 and EP4 receptors
- GC14879 AH 6809 An EP and DP receptor antagonist
-
GC17753
AH 7614
FFA4/GPR120 antagonist
- GC10146 AHU-377(Sacubitril) AHU-377(Sacubitril) (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM.
- GC35272 Ajmalicine A terpenoid indole alkaloid
- GC32405 AL 082D06 (D06) AL 082D06 (D06) is a selective, nonsteroidal glucocorticoid receptor (GR) antagonist with Ki of 210 nM.
-
GC16895
AL 8810
Antagonist of prostaglandin F2α (FP) receptor.
- GC16566 AL 8810 isopropyl ester lipid soluble, esterified prodrug form of AL 8810, a FP receptor antagonist
- GC31388 ALB-127158(a) ALB-127158(a) is a potent and selective melanin concentrating hormone 1 (MCH1) receptor antagonist.
- GC25046 Albiglutide Fragment Albiglutide fragment is one copy of a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).
- GC35282 Alexamorelin Met 1
- GC16740 Alfuzosin alpha-adrenergic blocker
- GC13730 Alfuzosin HCl Alfuzosin (SL 77499-10) hydrochloride is an orally active, selective and competitive α1-adrenoceptor antagonist.
- GC32558 Aligeron Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.
- GC62833 ALK4290 ALK4290 (AKST4290) is a potent and orally actively CCR3 inhibitor extracted from patent US20130261153A1, compound Example 2, with a Ki of 3.2 nM for hCCR3.
- GC25051 Alloxazine Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.
- GC10717 Almorexant OX1R/OX2R antagonist
- GC10050 Almorexant hydrochloride OX1R/OX2R antagonist
- GC15153 Almotriptan Malate 5-HT1B/1D-receptor agonist
- GC31054 Alniditan (Alnitidan) Alniditan (Alnitidan) (Alnitidan) is a potent 5-HT1B and 5-HT1D receptors agonist, with IC50s of 1.7 nM and 1.3 nM for h5-HT1B and h5-HT1D receptors in HEK293 cells, respectively.
- GC35301 Alosetron ((Z)-2-butenedioate) Alosetron (GR 68755) (Z)-2-butenedioate is a potent and highly selective serotonin 5-HT3 receptor antagonist.
- GC35302 Alosetron (Hydrochloride(1:X)) Alosetron (GR 68755) Hydrochloride(1:X) is a potent and highly selective serotonin 5-HT3 receptor antagonist.
- GC35303 Alosetron D3 Hydrochloride Alosetron D3 Hydrochloride (GR-68755C D3) is deuterium labeled Alosetron, which is a serotonin 5HT3-receptor antagonist.
- GC64265 Alosetron-13C,d3
- GC32905 Alprenolol ((RS)-Alprenolol) Alprenolol ((RS)-Alprenolol) ((RS)-Alprenolol ((RS)-Alprenolol); dl-Alprenolol ((RS)-Alprenolol)) is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol ((RS)-Alprenolol) is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent.
- GC14105 Alprenolol hydrochloride β-adrenoceptor and 5-HT1A receptor antagonist.
- GC17347 Alprostadil Alprostadil (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively.
- GC14030 Altanserin hydrochloride 5-HT2A receptor antagonist