Membrane Transporter/Ion Channel
- Piezo Channels(1)
- Aquaporins(1)
- AMPAR(62)
- ATPase(83)
- Calcium Channel(316)
- Cannabinoid Transporters(6)
- CFTR(41)
- Chloride Channels(13)
- GABA Receptor(196)
- Gardos Channel(1)
- Glucose Transporters(9)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(19)
- GTPase(21)
- Kv1.3(1)
- ICB(3)
- Lipophilic platinum complex(1)
- M2 ion Channel(1)
- MCT2(4)
- Monoamine transporter(17)
- Monocarboxylate Transporters(12)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(18)
- NKCC(7)
- NMDA Receptor(83)
- Nucleoside Transporters(4)
- Pannexin-1(4)
- P2X purinergic receptor(73)
- P-gp(14)
- Proton Pump(55)
- Potassium Channel(283)
- Sodium Channel(189)
- TRP Channel(157)
- TRPV1(11)
- URAT1(8)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(12)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(25)
- CRAC Channel(14)
- EAAT2(6)
- HCN Channel(5)
- Na+/HCO3- Cotransporter(2)
- Na+/K+ ATPase(34)
- P-glycoprotein(57)
- iGluR(166)
- nAChR(99)
- VDAC(2)
- GlyR(1)
Products for Membrane Transporter/Ion Channel
- Cat.No. Product Name Information
- GC42827 Apoptolidin Apoptolidin is an apoptosis inducer originally isolated from Nocardiopsis bacteria.
- GC50226 AR-C 141990 hydrochloride MCT1 inhibitor
- GC10680 AR-C155858 An inhibitor of MCT1 and 2
- GC34049 Aranidipine (MPC1304) Aranidipine (MPC1304) (MPC1304) is a Ca2+ channel antagonist with potent and long-lasting antihypertensive effects.
- GC14470 Arcaine sulfate NMDA antagonist
- GC63879 Arecaidine hydrochloride Arecaidine hydrochloride, a pyridine alkaloid, is a potent GABA uptake inhibitor.
- GC17225 ARL 67156 trisodium salt ARL67156 (FPL 67156) trisodium is a selective ecto-ATPase inhibitor.
- GC35407 Asivatrep Asivatrep (PAC-14028) is a potent and selective transient receptor potential vanilloid type I (TRPV1) antagonist.
- GC50115 ASP 7663 Selective TRPA1 activator
- GC38888 ASP2535 ASP2535 is a potent, orally bioavailable, selective, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.
- GC61960 ASP2905 ASP2905 is a potent and selective potassium channel Kv12.2 inhibitor encoded by the Kcnh3/BEC1 gene.
- GC45387 Aspergillimide Aspergillimide ((rel)-Aspergillimide), an anthelmintic metabolite, is isolated from okara that has been fermented with Aspergillus japonicas JV-23.
- GC16945 Astemizole anti-histamine compound, potent
- GC12945 Atazanavir An inhibitor of HIV-1 protease
- GC10240 Atazanavir sulfate (BMS-232632-05) An inhibitor of HIV-1 protease
- GC49421 Atorvastatin lactone-d5 An internal standard for the quantification of atorvastatin lactone
- GC11109 ATP disodium salt P2 purinoceptor agonist
- GC35421 ATP synthase inhibitor 1 ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels.
- GC38497 ATPA
- GC12721 ATPA GluR5 kainate receptor agonist
- GC46891 ATPA (hydrate) An agonist of GluR5
- GC12574 ATPγS tetralithium salt ATPγS (tetralithium salt) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A.
- GC15667 Atracurium Besylate Neuromuscular blocking agent
- GC39699 Aurintricarboxylic acid Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively.
-
GC19480
AUT1
Cell permeant modulator
- GC15099 Autocamtide-2-related inhibitory peptide inhibitor of calmodulin-dependent protein kinase II (CaM-kinase II, CaMKII)
- GC10974 AWD 131-138 AWD 131-138 (AWD 131-138) is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models.
- GC17375 AZ 10606120 dihydrochloride Potent P2X7 receptor antagonist
- GC18052 AZ 11645373 Human P2X7 antagonist,potent and selective
- GC63799 AZ194 AZ194 is a first-in-class, orally active inhibitor of CRMP2-Ubc9 interaction and inhibitor of NaV1.7 (IC50=1.2 μM).
- GC11010 AZD 3965 potent inhibitor of monocarboxylate transporter 1 (MCT1)
- GC64274 AZD-5672 AZD-5672 is an orally active, potent, and selective CCR5 antagonist (IC50=0.32 nM).
- GC31010 AZD-6280 AZD-6280 is a selective GABAA(α2/3) receptor modulator, used for treatment of generalized anxiety disorder.
- GC31674 AZD9056 hydrochloride AZD9056 hydrochloride is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing diseases.
- GC15101 Azelnidipine L-type calcium channel blocker;antihypertensive
- GC35451 Azelnidipine D7
- GC14515 Azimilide class III anti-arrhythmic drug
- GC35453 Azimilide Dihydrochloride A class III antiarrhythmic agent
- GC38738 Azosemide Azosemide, a sulfonamide loop diuretic, is a potent NKCC1 inhibitor with IC50s of 0.246??M and 0.197??M for hNKCC1A and NKCC1B, respectively.
- GC61493 Azumolene Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant.
- GC42893 Azumolene (sodium salt) Azumolene is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum.
- GC17597 Bafilomycin A1 Bafilomycin A1, a macrolide antibiotic isolated from the Streptomyces species, is an inhibitor of vacuolar H ATPase (V-ATPase).
- GC10934 Bafilomycin C1 vacuolar H+-ATPases (V-ATPases) inhibitor
- GC12302 Bafilomycin D vacuolar H+ ATPases (V-ATPases) inhibitor
- GC31990 Bamaluzole Bamaluzole is a GABA receptor agonist extracted from patent WO 2012064642 A1.
- GC31426 Bamaquimast (F 10126) Bamaquimast (F 10126) (F 10126; L 0042) is a potent antiasthmatic drug.
- GC35469 Barnidipine Barnidipine (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors.
- GC13289 Barnidipine (hydrochloride) calcium-channel blocker
- GC19057 Basmisanil Basmisanil is a highly selective GABAAα5 negative allosteric modulator.
- GC39344 BAY-1797 A P2X4receptor antagonist
- GC19000 BAY-588 BAY-588 is a glucose transporter inhibitor and derivative of BAY-876 .
-
GC19488
BAY-8002
BAY-8002 is a potent, selective, orally active inhibitor of monocarboxylate transporter 1 (MCT1)
- GC16516 BCH BCH (BCH) is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis.
- GC14276 BCTC vanilloid receptor 1 (TRPV1 receptor) antagonist
- GC13323 BDS I Kv3.4 potassium channel blocker, potent and reversible
- GC33723 Becampanel (AMP 397) Becampanel (AMP 397) (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent.
- GC50661 BeKm 1 BeKm 1 is a HERG (human ether-a-go-go-related gene) blocking compound.
- GC12414 Bemegride GABA receptor antagonist
- GC13888 Benidipine HCl Benidipine HCl is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension).
-
GC11693
Benzamil hydrochloride
Na+/Ca2+ exhanger (NCX) inhibitor
- GC49403 Benzarone An active metabolite of benzbromarone
- GC14339 Benzethonium Chloride Potent inhibitor of nAChRs
- GC13125 Benzocaine Sodium channel inhibitor
- GC25134 Benzocaine hydrochloride Benzocaine hydrochloride (Ethyl 4-aminobenzoate, Ethyl p-aminobenzoate) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
-
GC42919
Benzonatate
Benzonatate is a reversible voltage-gated sodium channel blocker.
- GC15533 Bepridil hydrochloride Calcium channel blocker
- GC39743 Bepridil hydrochloride hydrate Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a non-selective, long-acting Ca+ channel antagonist and Na+, K+ channel inhibitor, with antianginal and type I antiarrhythmic effects.
- GC35501 Beta-Eudesmol A sesquiterpene with diverse biological activities
- GC39546 Bevantolol hydrochloride A β1-AR antagonist
- GC14664 BHQ BHQ (DTBHQ), the indirect food additive, regulates the activity of 5-lipoxygenase as well as the activity of COX-2 (IC50=1.8 and 14.1 μM for 5-LO and COX-2, respectively) .
- GC34486 BI 01383298 An NaCT inhibitor
- GC34489 BI-749327 BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively.
- GC34492 BI-9627 An NHE1 inhibitor
- GC34494 Bifenazate An acaricide
- GC60642 Bifenthrin A synthetic pyrethroid insecticide
- GC33338 Biricodar (VX-710) Biricodar (VX-710) (VX-710) is a modulator of P-glycoprotein and MRP-1; shows effective chemosensitizing activity in multidrug resistant cells.
- GC10206 Bitopertin An inhibitor of GlyT1
- GC35527 Bitopertin R enantiomer Bitopertin R enantiomer (RG1678 R enantiomer; RO4917838 R enantiomer) is the R-enantiomer of Bitopertin.
- GC10094 BL 1249 K2P2.1 (TREK-1) channel opener
- GC64658 Bliretrigine Bliretrigine is a sodium channel blocker.
- GC60090 BLU-5937
- GC14239 BMS 191011 BKCa channel opener
- GC31405 BMS-191095 BMS-191095 is an activators of mitochondrial ATP-sensitive potassium (mitoKATP) channels.
- GC35538 BNC375 BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs with an EC50 of 1.9 μM.
-
GC42965
Bongkrekic Acid
An inhibitor of mitochondrial adenine nucleotide translocase
- GC62874 BPAM344 BPAM344 is a kainate receptor (KAR) subunits GluK1b, GluK2a, and GluK3a positive allosteric modulator (PAM).
- GC30537 BPO-27 racemate BPO-27 racemate is a potent CFTR inhibitor with an IC50 of 8 nM.
- GC64064 Bradanicline Bradanicline is a highly selective α7 nicotinic acetylcholine receptor (nAChR) agonist (humanα7 nAChR: EC50=17 nM; Ki= 1.4 nM).
-
GC17683
Brefeldin A
Brefeldin A (BFA) is a fungal macrocyclic lactone and a potent, reversible inhibitor of intracellular vesicle formation and protein trafficking between the endoplasmic reticulum (ER) and the Golgi apparatus.
- GC11565 Bretazenil GABAA benzodiazepine site partial agonist
- GC49740 Brevetoxin 3 A neurotoxin
- GC42976 Brevetoxin B Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates.
- GC12421 Brilliant blue G-250 Brilliant Blue G-250 is a dye commonly used for the visualization of proteins separated by SDS-PAGE, offering a simple staining procedure and high quantitation.
- GC30521 Broflanilide Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor, and inhibits S.
- GC25174 Brucine sulfate heptahydrate Brucine is an alkaloid that acts as an antagonist at glycine receptors and paralyzes inhibitory neurons.
- GC16833 BTB06584 F1F0 ATP synthases
- GC42984 BTC (potassium salt) BTC (potassium salt) is a low affinity calcium indicator (Kd approximately 7-26 μM) featuring many desirable properties for cellular calcium imaging, including long excitation wavelengths (400/485 nm), low sensitivity to Mg2+, and accuracy of ratiometric measurement.
- GC42985 BTC AM BTC AM is a cell-permeable acetoxy-methyl ester of BTC.
- GC50617 BTD Selective TRPC5 activator
- GN10365 Bufalin