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Membrane Transporter/Ion Channel

Products for  Membrane Transporter/Ion Channel

  1. Cat.No. Product Name Information
  2. GC12312 Cilnidipine Blocker of Dual L- and N-type calcium channel Cilnidipine  Chemical Structure
  3. GC50188 CIM 0216 Selective TRPM3 agonist CIM 0216  Chemical Structure
  4. GC11695 Cinnarizine antihistamine and calcium channel blocker Cinnarizine  Chemical Structure
  5. GC60709 Cinnarizine D8 An internal standard for the quantification of cinnarizine Cinnarizine D8  Chemical Structure
  6. GC14414 CIQ NMDA receptor potentiator CIQ  Chemical Structure
  7. GC31120 Cirsimaritin Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities. Cirsimaritin  Chemical Structure
  8. GC14453 cis-ACBD glutamate uptake inhibitor cis-ACBD  Chemical Structure
  9. GC11942 cis-ACPD NMDA receptor agonist and group II mGluR agonist cis-ACPD  Chemical Structure
  10. GC12095 cis-Ned 19 nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist cis-Ned 19  Chemical Structure
  11. GC12226 Cisatracurium Besylate Neuromuscular-blocking drug Cisatracurium Besylate  Chemical Structure
  12. GC41514 Citreoviridin Citreoviridin is a mycotoxin isolated from several Penicillium species that has been shown to inhibit the mitochondrial ATP synthetase system. Citreoviridin  Chemical Structure
  13. GC16188 CL 218872 Benzodiazepine agonist CL 218872  Chemical Structure
  14. GC15012 Cl-HIBO desensitising AMPA receptor agonist Cl-HIBO  Chemical Structure
  15. GC16128 Clevidipine Butyrate Clevidipine Butyrate is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension. Clevidipine Butyrate  Chemical Structure
  16. GC32587 Clofilium tosylate Clofilium tosylate, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3. Clofilium tosylate  Chemical Structure
  17. GC38758 Clomethiazole Chlormethiazole is an potent and orally active GABAA?agonist. Clomethiazole  Chemical Structure
  18. GC15411 Clopamide sodium/chloride cotransporters inhibitor Clopamide  Chemical Structure
  19. GC33851 Cloperastine fendizoate Cloperastine fendizoate inhibits the hERG K+ currents in a concentration-dependent manner with an IC50 value of 27 nM. Cloperastine fendizoate  Chemical Structure
  20. GC60718 Cloperastine hydrochloride Cloperastine hydrochloride inhibits the hERG K+ currents in a concentration-dependent manner with an IC50 value of 27 nM. Cloperastine hydrochloride  Chemical Structure
  21. GC50127 CLP 257 Selective KCC2 activator CLP 257  Chemical Structure
  22. GC35713 CLP290 A prodrug form of CLP 257 CLP290  Chemical Structure
  23. GC19107 CM-4620 CM-4620 (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor, with IC50s of 119 nM and 895 nM for Orai1/STIM1 and Orai2/STIM1 channels, respectively. CM-4620  Chemical Structure
  24. GC13290 CMPDA positive allosteric modulator of AMPA receptors CMPDA  Chemical Structure
  25. GC50306 CMPI hydrochloride Potent positive allosteric modulator of α4β2 nAChRs; also inhibitor of (α4)2(β2)3, muscle-type and Torpedo nAChRs CMPI hydrochloride  Chemical Structure
  26. GC11799 CNQX CNQX is an effective competitive antagonist of AMPA/kainate receptors, with IC50 values of 0.3µM and 1.5µM, respectively.. CNQX  Chemical Structure
  27. GC14480 CNQX disodium salt CNQX disodium salt (FG9065 disodium) is a potent and competitive AMPA/kainate receptor antagonist with IC50s of 0.3 μM and 1.5 μM, respectively. CNQX disodium salt  Chemical Structure
  28. GC32553 CNS-5161 hydrochloride (CNS 5161A) CNS-5161 hydrochloride (CNS 5161A) is a novel NMDA ion-channel antagonist that interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate. CNS-5161 hydrochloride (CNS 5161A)  Chemical Structure
  29. GC10792 Co 101244 hydrochloride NR2B-containing NMDA receptor antagonist Co 101244 hydrochloride  Chemical Structure
  30. GC16182 Co 102862 voltage-gated sodium channel blocker Co 102862  Chemical Structure
  31. GC63868 COG 133 TFA COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA  Chemical Structure
  32. GC16899 Coluracetam Nootropic agent of the racetam family Coluracetam  Chemical Structure
  33. GC43306 Compound C108 Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation. Compound C108  Chemical Structure
  34. GC13714 Conantokin G NR2B-selective NMDA receptor antagonist Conantokin G  Chemical Structure
  35. GC12944 Conantokin-R non-competitive NMDA receptor antagonist Conantokin-R  Chemical Structure
  36. GC15156 Conantokin-T Non-competitive NMDA receptor antagonist Conantokin-T  Chemical Structure
  37. GC17519 Concanamycin A

    V-type (vacuolar) H+-ATPase inhibitor

    Concanamycin A  Chemical Structure
  38. GC13270 Congo Red VGlut inhibitor Congo Red  Chemical Structure
  39. GC35727 Coniferyl ferulate

    A monolignal conjugate with diverse biological activities

    Coniferyl ferulate  Chemical Structure
  40. GC39701 Convallatoxin Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin  Chemical Structure
  41. GC17592 CP 100356 hydrochloride P-glycoprotein (P-gp) inhibitor CP 100356 hydrochloride  Chemical Structure
  42. GC17595 CP 339818 hydrochloride KV1.3 channel antagonist CP 339818 hydrochloride  Chemical Structure
  43. GC12589 CP 465022 hydrochloride AMPA receptor antagonist, non-competitive and selective CP 465022 hydrochloride  Chemical Structure
  44. GC35738 CP-060 CP-?060 is a potent Ca2+ antagonist, inhibits Ca2+ overload and possesses antioxidant and cardioprotective activities. CP-060  Chemical Structure
  45. GC31052 CP-409092 CP-409092 is a partial agonist of GABAA receptor, with anti-anxiety activity. CP-409092  Chemical Structure
  46. GC38387 CP-409092 hydrochloride CP-409092 hydrochloride is a partial agonist of GABAA receptor, with anti-anxiety activity. CP-409092 hydrochloride  Chemical Structure
  47. GC12742 CP-465022 (maleate) AMPA antagonist CP-465022 (maleate)  Chemical Structure
  48. GC63582 CP-601927 CP-601927 is a selective α4β2 nicotinic acetylcholine receptor (nAChR) partial agonist (Ki=1.2 nM; EC50=2.6 μM). CP-601927  Chemical Structure
  49. GC63583 CP-601932 CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (Ki=21?nM; EC50=~ 3?μM). CP-601932  Chemical Structure
  50. GC31852 CRAC intermediate 1 CRAC intermediate 1 is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors, detailed information can be found in Patent WO 2010122089 A1, intermediate 9. CRAC intermediate 1  Chemical Structure
  51. GC30361 CRAC intermediate 2 CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis, extracted from patent WO 2013059666A1. CRAC intermediate 2  Chemical Structure
  52. GC67925 Crinecerfont hydrochloride Crinecerfont hydrochloride  Chemical Structure
  53. GC70055 Crocetin meglumine

    Crocetin (Transcrocetin) meglumine is extracted from saffron (Crocus sativus L.) and is a highly affinity NMDA receptor antagonist.

    Crocetin meglumine  Chemical Structure
  54. GC14116 Cromakalim Kir6 (KATP) channel opener Cromakalim  Chemical Structure
  55. GC17690 Cromolyn sodium Mast cell membrane stabilizer Cromolyn sodium  Chemical Structure
  56. GC31834 CV-159 CV-159 is a unique dihydropyridine Ca2+ antagonist with an anti-calmodulin (CaM) action, and has antiinflammatory activities. CV-159  Chemical Structure
  57. GC49410 CVT-2738 An active metabolite of ranolazine CVT-2738  Chemical Structure
  58. GC14495 CX 546 AMPA receptor potentiator CX 546  Chemical Structure
  59. GC50111 CX 614 Positive allosteric modulator of AMPA receptors CX 614  Chemical Structure
  60. GC64244 CX 717 CX 717 is a positive allosteric modulator of AMPA receptor. CX 717  Chemical Structure
  61. GC63967 Cycleanine Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine  Chemical Structure
  62. GC62179 Cyclic ADP-ribose Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase. Cyclic ADP-ribose  Chemical Structure
  63. GC43338 Cyclic ADP-Ribose (ammonium salt) Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types. Cyclic ADP-Ribose (ammonium salt)  Chemical Structure
  64. GC61792 Cyclic ADP-ribose ammonium Cyclic ADP-ribose ammonium  Chemical Structure
  65. GC31209 Cyclodrine hydrochloride Cyclodrine hydrochloride is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist. Cyclodrine hydrochloride  Chemical Structure
  66. GC61751 Cycloleucine Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation. Cycloleucine  Chemical Structure
  67. GC10268 Cyclopiazonic acid

    sarcoplasmic reticulum Ca2+-ATPase inhibitor

    Cyclopiazonic acid  Chemical Structure
  68. GC12207 Cyclothiazide positive allosteric modulator of AMPA receptors Cyclothiazide  Chemical Structure
  69. GC47155 Cyfluthrin A pyrethroid insecticide Cyfluthrin  Chemical Structure
  70. GC47158 Cypermethrin A type II pyrethroid insecticide Cypermethrin  Chemical Structure
  71. GC16144 CyPPA Activator of small conductance Ca2+-activated K+ channels CyPPA  Chemical Structure
  72. GN10126 Cytisine Cytisine  Chemical Structure
  73. GC33158 D-3263 D-3263 is an agonist of transient receptor potential melastatin member 8 (TRPM8) with potential antineoplastic activity. D-3263  Chemical Structure
  74. GC32961 D-3263 hydrochloride D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist. D-3263 hydrochloride  Chemical Structure
  75. GC16315 D-AP5

    A NMDA antagonist

    D-AP5  Chemical Structure
  76. GC15112 D-AP7 NMDA receptor antagonist D-AP7  Chemical Structure
  77. GC10043 D-CPP-ene NMDA antagonist D-CPP-ene  Chemical Structure
  78. GC67739 D-erythro-Sphingosine hydrochloride D-erythro-Sphingosine hydrochloride  Chemical Structure
  79. GC50670 D-GsMTx4 D-GsMTx4  Chemical Structure
  80. GC43516 D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt) D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)  Chemical Structure
  81. GC43522 D-myo-Inositol-1,4,5-triphosphate (potassium salt) D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C (PLC) mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. D-myo-Inositol-1,4,5-triphosphate (potassium salt)  Chemical Structure
  82. GC43523 D-myo-Inositol-1,4,5-triphosphate (sodium salt) Primary intracellular IP3 receptor agonist D-myo-Inositol-1,4,5-triphosphate (sodium salt)  Chemical Structure
  83. GC43524 D-myo-Inositol-1,4,6-triphosphate (sodium salt) D-myo-Inositol-1,4,6-phosphate (Ins(1,4,6)-P3) is a member of the inositol phosphate (InsP) family that play critical roles as small, soluble second messengers in the transmission of cellular signals. D-myo-Inositol-1,4,6-triphosphate (sodium salt)  Chemical Structure
  84. GC60797 D-Tubocurarine chloride pentahydrate

    D-Tubocurarine chloride pentahydrate is the chloride salt form of Tubocurarine, a nicotinic acetylcholine receptors (AChR) antagonist, and can be used as a skeletal muscle relaxant during surgery or mechanical ventilation.

    D-Tubocurarine chloride pentahydrate  Chemical Structure
  85. GC18583 D-α-Hydroxyglutaric Acid Over-produced in the human neurometabolic disease D-2-HGA D-α-Hydroxyglutaric Acid  Chemical Structure
  86. GC30930 DAA-1106 A TSPO agonist DAA-1106  Chemical Structure
  87. GC67747 Dalazatide TFA Dalazatide TFA  Chemical Structure
  88. GC30054 Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate)  Chemical Structure
  89. GC15868 Dantrolene, sodium salt Dantrolene, sodium salt is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene, sodium salt  Chemical Structure
  90. GC31301 Darodipine (PY 108-068) Darodipine (PY 108-068) (PY 108-068, PY-108068) is a potent calcium channel antagonist. Darodipine (PY 108-068)  Chemical Structure
  91. GC33003 Daurisoline ((R,R)-Daurisoline) Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor and also an autophagy blocker. Daurisoline ((R,R)-Daurisoline)  Chemical Structure
  92. GC43383 DBO-83 DBO-83 is an agonist of nicotinic acetylcholine receptors (nAChRs) with antinociceptive and anti-amnesic activities. DBO-83  Chemical Structure
  93. GC16795 DCA DCA is a metabolic regulator in cancer cells' mitochondria with anticancer activity. DCA inhibits PDHK, resulting in decreased lactic acid in the tumor microenvironment. DCA increases reactive oxygen species (ROS) generation and promotes cancer cell apoptosis. DCA also works as NKCC inhibitor. DCA  Chemical Structure
  94. GC15750 DCEBIO Stimulates Cl- secretion DCEBIO  Chemical Structure
  95. GC14073 DCPIB volume-sensitive anion channel (VSAC) and and ICl,swell blocker DCPIB  Chemical Structure
  96. GC16255 Decamethonium Bromide Nicotinic AChR partial agonist Decamethonium Bromide  Chemical Structure
  97. GC43391 Decanoic Acid (sodium salt) Decanoic acid is a saturated medium-chain fatty acid that contains 10 carbons. Decanoic Acid (sodium salt)  Chemical Structure
  98. GC17127 Decynium 22 Pseudoisocyanine (iodide) is a pan inhibitor of monoamine transporters and organic cation transporters with antidepressant-like activity. Decynium 22  Chemical Structure
  99. GC43399 Dehydro Amlodipine (fumarate) Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine. Dehydro Amlodipine (fumarate)  Chemical Structure
  100. GC11070 Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, together represent the most abundant steroid hormones in the human body . Dehydroepiandrosterone (DHEA)  Chemical Structure
  101. GC33486 Dehydronitrosonisoldipine

    A calcium channel antagonist

    Dehydronitrosonisoldipine  Chemical Structure

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