Membrane Transporter/Ion Channel
- Piezo Channels(1)
- Aquaporins(1)
- AMPAR(62)
- ATPase(83)
- Calcium Channel(316)
- Cannabinoid Transporters(6)
- CFTR(41)
- Chloride Channels(13)
- GABA Receptor(196)
- Gardos Channel(1)
- Glucose Transporters(9)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(19)
- GTPase(21)
- Kv1.3(1)
- ICB(3)
- Lipophilic platinum complex(1)
- M2 ion Channel(1)
- MCT2(4)
- Monoamine transporter(17)
- Monocarboxylate Transporters(12)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(18)
- NKCC(7)
- NMDA Receptor(83)
- Nucleoside Transporters(4)
- Pannexin-1(4)
- P2X purinergic receptor(73)
- P-gp(14)
- Proton Pump(55)
- Potassium Channel(283)
- Sodium Channel(189)
- TRP Channel(157)
- TRPV1(11)
- URAT1(8)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(12)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(25)
- CRAC Channel(14)
- EAAT2(6)
- HCN Channel(5)
- Na+/HCO3- Cotransporter(2)
- Na+/K+ ATPase(34)
- P-glycoprotein(57)
- iGluR(166)
- nAChR(99)
- VDAC(2)
- GlyR(1)
Products for Membrane Transporter/Ion Channel
- Cat.No. Product Name Information
- GC12312 Cilnidipine Blocker of Dual L- and N-type calcium channel
- GC50188 CIM 0216 Selective TRPM3 agonist
- GC11695 Cinnarizine antihistamine and calcium channel blocker
- GC60709 Cinnarizine D8 An internal standard for the quantification of cinnarizine
- GC14414 CIQ NMDA receptor potentiator
- GC31120 Cirsimaritin Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities.
- GC14453 cis-ACBD glutamate uptake inhibitor
- GC11942 cis-ACPD NMDA receptor agonist and group II mGluR agonist
- GC12095 cis-Ned 19 nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist
- GC12226 Cisatracurium Besylate Neuromuscular-blocking drug
- GC41514 Citreoviridin Citreoviridin is a mycotoxin isolated from several Penicillium species that has been shown to inhibit the mitochondrial ATP synthetase system.
- GC16188 CL 218872 Benzodiazepine agonist
- GC15012 Cl-HIBO desensitising AMPA receptor agonist
- GC16128 Clevidipine Butyrate Clevidipine Butyrate is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension.
- GC32587 Clofilium tosylate Clofilium tosylate, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3.
- GC38758 Clomethiazole Chlormethiazole is an potent and orally active GABAA?agonist.
- GC15411 Clopamide sodium/chloride cotransporters inhibitor
- GC33851 Cloperastine fendizoate Cloperastine fendizoate inhibits the hERG K+ currents in a concentration-dependent manner with an IC50 value of 27 nM.
- GC60718 Cloperastine hydrochloride Cloperastine hydrochloride inhibits the hERG K+ currents in a concentration-dependent manner with an IC50 value of 27 nM.
- GC50127 CLP 257 Selective KCC2 activator
- GC35713 CLP290 A prodrug form of CLP 257
- GC19107 CM-4620 CM-4620 (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor, with IC50s of 119 nM and 895 nM for Orai1/STIM1 and Orai2/STIM1 channels, respectively.
- GC13290 CMPDA positive allosteric modulator of AMPA receptors
- GC50306 CMPI hydrochloride Potent positive allosteric modulator of α4β2 nAChRs; also inhibitor of (α4)2(β2)3, muscle-type and Torpedo nAChRs
- GC11799 CNQX CNQX is an effective competitive antagonist of AMPA/kainate receptors, with IC50 values of 0.3µM and 1.5µM, respectively..
- GC14480 CNQX disodium salt CNQX disodium salt (FG9065 disodium) is a potent and competitive AMPA/kainate receptor antagonist with IC50s of 0.3 μM and 1.5 μM, respectively.
- GC32553 CNS-5161 hydrochloride (CNS 5161A) CNS-5161 hydrochloride (CNS 5161A) is a novel NMDA ion-channel antagonist that interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate.
- GC10792 Co 101244 hydrochloride NR2B-containing NMDA receptor antagonist
- GC16182 Co 102862 voltage-gated sodium channel blocker
- GC63868 COG 133 TFA COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide.
- GC16899 Coluracetam Nootropic agent of the racetam family
- GC43306 Compound C108 Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation.
- GC13714 Conantokin G NR2B-selective NMDA receptor antagonist
- GC12944 Conantokin-R non-competitive NMDA receptor antagonist
- GC15156 Conantokin-T Non-competitive NMDA receptor antagonist
-
GC17519
Concanamycin A
V-type (vacuolar) H+-ATPase inhibitor
- GC13270 Congo Red VGlut inhibitor
-
GC35727
Coniferyl ferulate
A monolignal conjugate with diverse biological activities
- GC39701 Convallatoxin Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde.
- GC17592 CP 100356 hydrochloride P-glycoprotein (P-gp) inhibitor
- GC17595 CP 339818 hydrochloride KV1.3 channel antagonist
- GC12589 CP 465022 hydrochloride AMPA receptor antagonist, non-competitive and selective
- GC35738 CP-060 CP-?060 is a potent Ca2+ antagonist, inhibits Ca2+ overload and possesses antioxidant and cardioprotective activities.
- GC31052 CP-409092 CP-409092 is a partial agonist of GABAA receptor, with anti-anxiety activity.
- GC38387 CP-409092 hydrochloride CP-409092 hydrochloride is a partial agonist of GABAA receptor, with anti-anxiety activity.
- GC12742 CP-465022 (maleate) AMPA antagonist
- GC63582 CP-601927 CP-601927 is a selective α4β2 nicotinic acetylcholine receptor (nAChR) partial agonist (Ki=1.2 nM; EC50=2.6 μM).
- GC63583 CP-601932 CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (Ki=21?nM; EC50=~ 3?μM).
- GC31852 CRAC intermediate 1 CRAC intermediate 1 is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors, detailed information can be found in Patent WO 2010122089 A1, intermediate 9.
- GC30361 CRAC intermediate 2 CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis, extracted from patent WO 2013059666A1.
- GC67925 Crinecerfont hydrochloride
-
GC70055
Crocetin meglumine
Crocetin (Transcrocetin) meglumine is extracted from saffron (Crocus sativus L.) and is a highly affinity NMDA receptor antagonist.
- GC14116 Cromakalim Kir6 (KATP) channel opener
- GC17690 Cromolyn sodium Mast cell membrane stabilizer
- GC31834 CV-159 CV-159 is a unique dihydropyridine Ca2+ antagonist with an anti-calmodulin (CaM) action, and has antiinflammatory activities.
- GC49410 CVT-2738 An active metabolite of ranolazine
- GC14495 CX 546 AMPA receptor potentiator
- GC50111 CX 614 Positive allosteric modulator of AMPA receptors
- GC64244 CX 717 CX 717 is a positive allosteric modulator of AMPA receptor.
- GC63967 Cycleanine Cycleanine is a potent vascular selective Calcium antagonist.
- GC62179 Cyclic ADP-ribose Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase.
- GC43338 Cyclic ADP-Ribose (ammonium salt) Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types.
- GC61792 Cyclic ADP-ribose ammonium
- GC31209 Cyclodrine hydrochloride Cyclodrine hydrochloride is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.
- GC61751 Cycloleucine Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation.
-
GC10268
Cyclopiazonic acid
sarcoplasmic reticulum Ca2+-ATPase inhibitor
- GC12207 Cyclothiazide positive allosteric modulator of AMPA receptors
- GC47155 Cyfluthrin A pyrethroid insecticide
- GC47158 Cypermethrin A type II pyrethroid insecticide
- GC16144 CyPPA Activator of small conductance Ca2+-activated K+ channels
- GN10126 Cytisine
- GC33158 D-3263 D-3263 is an agonist of transient receptor potential melastatin member 8 (TRPM8) with potential antineoplastic activity.
- GC32961 D-3263 hydrochloride D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist.
-
GC16315
D-AP5
A NMDA antagonist
- GC15112 D-AP7 NMDA receptor antagonist
- GC10043 D-CPP-ene NMDA antagonist
- GC67739 D-erythro-Sphingosine hydrochloride
- GC50670 D-GsMTx4
- GC43516 D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt) D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase.
- GC43522 D-myo-Inositol-1,4,5-triphosphate (potassium salt) D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C (PLC) mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate.
- GC43523 D-myo-Inositol-1,4,5-triphosphate (sodium salt) Primary intracellular IP3 receptor agonist
- GC43524 D-myo-Inositol-1,4,6-triphosphate (sodium salt) D-myo-Inositol-1,4,6-phosphate (Ins(1,4,6)-P3) is a member of the inositol phosphate (InsP) family that play critical roles as small, soluble second messengers in the transmission of cellular signals.
-
GC60797
D-Tubocurarine chloride pentahydrate
D-Tubocurarine chloride pentahydrate is the chloride salt form of Tubocurarine, a nicotinic acetylcholine receptors (AChR) antagonist, and can be used as a skeletal muscle relaxant during surgery or mechanical ventilation.
- GC18583 D-α-Hydroxyglutaric Acid Over-produced in the human neurometabolic disease D-2-HGA
- GC30930 DAA-1106 A TSPO agonist
- GC67747 Dalazatide TFA
- GC30054 Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.
- GC15868 Dantrolene, sodium salt Dantrolene, sodium salt is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm.
- GC31301 Darodipine (PY 108-068) Darodipine (PY 108-068) (PY 108-068, PY-108068) is a potent calcium channel antagonist.
- GC33003 Daurisoline ((R,R)-Daurisoline) Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor and also an autophagy blocker.
- GC43383 DBO-83 DBO-83 is an agonist of nicotinic acetylcholine receptors (nAChRs) with antinociceptive and anti-amnesic activities.
- GC16795 DCA DCA is a metabolic regulator in cancer cells' mitochondria with anticancer activity. DCA inhibits PDHK, resulting in decreased lactic acid in the tumor microenvironment. DCA increases reactive oxygen species (ROS) generation and promotes cancer cell apoptosis. DCA also works as NKCC inhibitor.
- GC15750 DCEBIO Stimulates Cl- secretion
- GC14073 DCPIB volume-sensitive anion channel (VSAC) and and ICl,swell blocker
- GC16255 Decamethonium Bromide Nicotinic AChR partial agonist
- GC43391 Decanoic Acid (sodium salt) Decanoic acid is a saturated medium-chain fatty acid that contains 10 carbons.
- GC17127 Decynium 22 Pseudoisocyanine (iodide) is a pan inhibitor of monoamine transporters and organic cation transporters with antidepressant-like activity.
- GC43399 Dehydro Amlodipine (fumarate) Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine.
- GC11070 Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, together represent the most abundant steroid hormones in the human body .
-
GC33486
Dehydronitrosonisoldipine
A calcium channel antagonist