Membrane Transporter/Ion Channel
- Piezo Channels(1)
- Aquaporins(1)
- AMPAR(62)
- ATPase(83)
- Calcium Channel(316)
- Cannabinoid Transporters(6)
- CFTR(41)
- Chloride Channels(13)
- GABA Receptor(196)
- Gardos Channel(1)
- Glucose Transporters(9)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(19)
- GTPase(21)
- Kv1.3(1)
- ICB(3)
- Lipophilic platinum complex(1)
- M2 ion Channel(1)
- MCT2(4)
- Monoamine transporter(17)
- Monocarboxylate Transporters(12)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(18)
- NKCC(7)
- NMDA Receptor(83)
- Nucleoside Transporters(4)
- Pannexin-1(4)
- P2X purinergic receptor(73)
- P-gp(14)
- Proton Pump(55)
- Potassium Channel(283)
- Sodium Channel(189)
- TRP Channel(157)
- TRPV1(11)
- URAT1(8)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(12)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(25)
- CRAC Channel(14)
- EAAT2(6)
- HCN Channel(5)
- Na+/HCO3- Cotransporter(2)
- Na+/K+ ATPase(34)
- P-glycoprotein(57)
- iGluR(166)
- nAChR(99)
- VDAC(2)
- GlyR(1)
Products for Membrane Transporter/Ion Channel
- Cat.No. Product Name Information
- GC13733 A 438079 hydrochloride An antagonist of the nucleotide receptor P2X7
- GC17091 A 784168 TRPV1 antagonist,potent and selective
- GC17870 A 804598 P2X7 antagonist,potent and selective
- GC15434 A 839977 P2X7 antagonist,potent and selective
- GC50088 A 85380 dihydrochloride High affinity and selective α4β2 nAChR agonist
- GC14481 A 887826 voltage-dependent Nav1.8 sodium channel blocker
- GC11701 A 967079 Selective TRPA1 channel blocker
- GC30837 A-1165442 A-1165442 is a potent, competitive and orally available TRPV1 antagonist with an IC50 of 9 nM for human TRPV1.
- GC17710 A-317491 A P2X3 and P2X2/3 receptor antagonist
- GC35211 A-317491 sodium salt hydrate A-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively.
- GC11178 A-7 hydrochloride calmodulin antagonist
- GC11842 A-740003 A selective P2X7 antagonist
- GC15701 A-803467 NaV1.8 channel blocker,potent and selective
- GC15014 A-867744 A positive allosteric modulator of α7 nAChRs
-
GC11200
A23187
A23187, free acid is a Ca2+ ionophore
- GC39335 A2764 dihydrochloride A2764 dihydrochloride is a highly selective inhibitor of TRESK (TWIK-related spinal cord K+ channel, K2P18.1), which has moderate inhibitory effects on TREK-1 and TALK-1.
- GC60545 A2793 A2793 is an efficient dual TWIK-related acid-sensitive K+ channel (TASK)-1/TRESK inhibitor, with an IC50 of 6.8 μM for mTRESK.
- GC10641 AA 29504 GABAA receptor modulator
- GC50167 AAQ chloride Photoswitchable Kv channel blocker
- GC62823 Abeprazan Abeprazan (DWP14012) is a potassium-competitive acid blocker.
- GC65377 Abeprazan hydrochloride Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker.
- GC35222 ABT-239 ABT-239 is a novel, highly efficacious, non-imidazole?class of H3R antagonist and a transient receptor potential vanilloid type 1 (TRPV1) antagonist.
- GC60549 ABT-418 hydrochloride ABT-418 hydrochloride is a potent and selective agonist of nAChRs with cognitive enhancing and anxiolytic activities.
- GC19016 ABT-639 ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker.
- GC33720 ABT-639 hydrochloride ABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker.
- GC40860 AC1903 AC1903 is an inhibitor of transient receptor potential canonical channel 5 (TRPC5; IC50 = 14.7 μM).
- GN10812 Acacetin
- GC11286 ACBC ACBC is a NMDA receptor partial agonist acting at the glycine site, NR1.
- GC14712 ACET ACET (ACET) is a highly potent and selective kainate receptor GluK1 (GluR5) antagonist, with a Kb value of 1.4 nM.
- GC18262 Acetamiprid A neonicotinoid insecticide
- GC14142 Acetylcholine Chloride Major transmitter at many nervous sites
- GC18474 Acetyldigitoxin Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes.
- GC30927 Acevaltrate Acevaltrate inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50s of 22.8 μM and 42.3 μM, respectively.
- GC31100 ACT-709478 ACT-709478 is a potent, selective, orally active, and brain penetrating T-type calcium channel blocker.
- GC19729 Adenosine 5′-diphosphoribose sodium Adenosine 5′-diphosphoribose sodium (ADP ribose sodium) is a nicotinamide adenine nucleotide (NAD+) metabolite.
- GC49231 Adenylosuccinic Acid (ammonium salt) A purine nucleotide and an intermediate in the purine nucleotide cycle
- GC13542 Adiphenine HCl Adiphenine HCl is a non-competitive inhibitor of nicotinic acetylcholine receptor (nAChR), with an IC50s of 1.9, 1.8, 3.7, and 6.3 μM for α1, α3β4, α4β2, and α4β4, respectively.
- GC19021 Adjudin Adjudin is an extensively studied male contraceptive with a superior mitochondria-inhibitory effect.
- GC11315 ADWX 1 Kv1.3 channel blocker,potent and selective
- GC32672 AE0047 Hydrochloride AE0047 Hydrochloride is a calcium blocker, used in the research of hypertensive disease.
- GC19022 AF-353 AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0).
- GC30844 Afloqualone An Analytical Reference Standard
- GC39248 Afoxolaner An isoxazoline insecticide and acaricide
- GC14867 Agitoxin 2 Shaker K+ channel blocker, potent
- GC35273 Ajmaline
- GC45378 Alaproclate (hydrochloride)
- GC30371 Alisol F Alisol F is a triterpene isolated from Alisma orientalis, has immunosuppressive and anti-virus functions.
- GC40476 Allethrin Allethrin is a pyrethroid insecticide and modulator of voltage-gated sodium channels (NaV).
- GC35293 Allocryptopine Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Corydalis decumbens (Thunb.
- GC46831 Alloisolithocholic Acid Alloisolithocholic Acid (3β-Hydroxy-5α-cholanic acid), a derivative of Lithocholic acid, is a T cell regulator.
- GC14192 Allopregnanolone Allopregnanolone, a 3alpha, 5alpha progesterone metabolite, acts as a potent allosteric modulator of the γ-aminobutyric acid type A (GABAA) receptor, exerts antidepressant and neuroprotective action.
- GC30891 Almitrine mesylate (Almitrine bismesylate) Almitrine mesylate (Almitrine bismesylate), a peripheral chemoreceptor agonist, inhibits selectively the Ca2+-dependent K+ channel.
- GC32673 Almokalant (H 234/09) Almokalant (H 234/09) is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current.
- GC30983 alpha-Asarone (α-Asarone) alpha-Asarone (α-Asarone) (α-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.
- GC13515 Alphaxalone activates and potentiates GABAA receptor-activated membrane current (IGABA)
- GC15467 ALX 5407 hydrochloride GlyT1 inhibitor,selective non-transportable
- GC12972 AM 1172 Inhibitor of anandamide uptake and FAAH,potent and selective
- GC50475 AM 12 TRPC5 inhibitor
- GC12071 AM 404 Anandamide transport inhibitor
- GC10943 AM 92016 hydrochloride Potassium channel blocker
- GC19025 AM-0902 AM-0902 is a potent, selective transient receptor potential A1 (TRPA1) antagonist with IC50s of 71 and 131 nM for rTRPA1 and hTRPA1, respectively.
- GC30917 AM-2099 AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 with an IC50 of 0.16 μM for human Nav1.7.
- GC15458 Ambroxol HCl Ambroxol HCl (NA-872 hydrochloride), an active metabolite of the prodrug Bromhexine, has potent expectorant effects.
- GC50058 AMG 21629 Potent and selective TRPV1 antagonist
- GC65611 AMG 333 AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM.
- GC11926 AMG 9810 TRPV1 antagonist
- GC13003 AMG-517 TRPV1 antagonist,potent and highly selective
- GC35316 AMG2850 AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist.
- GC31431 Amiloride (MK-870) Amiloride (MK-870) (MK-870) is an inhibitor of both epithelial sodium channel (ENaC[1]) and urokinase-type plasminogen activator receptor (uTPA[2]).
- GC17853 Amiloride HCl Amiloride HCl (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel (ENaC[1]) and urokinase-type plasminogen activator receptor (uTPA[2]).
- GC12051 Amiloride HCl dihydrate Amiloride HCl dihydrate (MK-870 hydrochloride dihydrate) is an inhibitor of both epithelial sodium channel (ENaC[1]) and urokinase-type plasminogen activator receptor (uTPA[2]).
- GC34064 Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride) Aminooxyacetic acid (Carboxymethoxylamine) hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T.
- GC35322 Amiodarone Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM.
- GC11432 Amiodarone HCl Amiodarone HCl, a benzofuran-based Class III antiarrhythmic agent, inhibits WT outwardIhERG tails with an IC50 of ~45 nM.
- GC18274 Amiprofos-methyl Amiprofos-methyl (APM) is a phosphoric amide herbicide.
- GC13723 Amitriptyline HCl Amitriptyline HCl is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively.
- GC13523 Amlodipine Calcium channel blocker
- GC13146 Amlodipine Besylate Block of L-type calcium channel
- GC35325 Amlodipine maleate Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent.
- GC50334 AMP PNP AMP PNP (Adenylyl-imidodiphosphate tetralithium) is a non-hydrolysable analogue of ATP and inhibits KATP channels.
- GC62840 AMPA receptor modulator-2 AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor.
- GC68438 AMPA receptor modulator-3
- GC13164 Ampalex An AMPA receptor modulator
- GC14537 AMTB hydrochloride TRPM8 channel blocker
- GC30866 Anabasine ((S)-Anabasine) Anabasine ((S)-Anabasine) ((S)-Anabasine ((S)-Anabasine)) is an alkaloid that found as a minor component in tobacco (Nicotiana).
- GC39254 Anatabine dicitrate Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier.
- GC46086 Ani 9 An inhibitor of ANO1
- GC32566 Anipamil Anipamil is a long-acting calcium channel blocker, used for the treatment of cardiovascular disease.
- GC17695 Aniracetam Nootropic drug for senile dementia
- GC18203 Annonacin Annonacin is a potent and lipophilic acetogenin from A.
- GC31141 Antihistamine-1 Antihistamine-1 is a H1-antihistamine (Ki=6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM, respectively.
- GC50471 AP 14145 hydrochloride KCa2 channel negative allosteric modulator
-
GC18020
AP 18
Reversible TRPA1 channel blocker
- GC42821 AP219 AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria.
- GC42823 AP39 AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria.
- GC14893 Apamin small-conductance Ca2+-activated K+-channel (KCa2, SK) inhibitor
- GC38557 Apamin TFA Apamin TFA (Apamine TFA) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca2+-activated K+ (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity.
- GC17168 APETx2 acid-sensing ion channel 3 (ASIC3) channel blocker
- GC65272 APETx2 TFA APETx2 TFA, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC50 of 63 nM.
- GC30911 Apimostinel (NRX-1074) Apimostinel (NRX-1074) (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist.