Kategorie: Caspase Aminopeptidase ACE Calpains Carboxypeptidase Cathepsin DPP-4 Elastase Gamma Secretase HCV Protease HSP HIV Integrase HIV Protease MMP NS3/4a protease Serine Protease Thrombin Urokinase Other Proteases Tyrosinases 15-PGDH Acetyl-CoA Carboxylase Acyltransferase Aldehyde Dehydrogenase (ALDH) Aminoacyl-tRNA Synthetase ATGL Dipeptidyl Peptidase Drug Metabolite E1/E2/E3 Enzyme Endogenous Metabolite FABP Farnesyl Transferase Glutaminase Glutathione Peroxidase Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase Lipoxygenase Mitochondrial Metabolism NEDD8-activating Enzyme Neprilysin PAI-1 Ser/Thr Protease Tryptophan Hydroxylase Xanthine Oxidase MALT1 PCSK9 Pyroptosis Apoptosis Inducers Bax Bcl-2 Family Bcl-xL c-RET IAP KEAP1-Nrf2 MDM2 p53 PC-PLC PKD RasGAP (Ras- P21) Survivin Thymidylate Synthase TNF-α Other Apoptosis APC PD-1/PD-L1 interaction ASK1 RIP kinase FKBP Bromodomain Aurora Kinase DNA Methyltransferase HDAC Histone Acetyltransferases Histone Demethylases Histone Methyltransferase HIF JAK PARP Pim Protein Ser/Thr Phosphatases RNA Polymerase Sirtuin Sphingosine Kinase-2 Polycomb repressive complex SUMOylation PAD Epigenetic Reader Domain MicroRNA Protein Arginine Deiminase Citrullination DNA/RNA Demethylation Histone Deacetylation Histones/Histone Peptides PRMT PPAR Sterol Biosynthesis 5-alpha Reductase 5-Lipoxygenase Adenosine Deaminase C14ɑ demethylase Carbonic Anhydrase CETP Cholesterol absorption CPT1 CYP3A/CYP450 Dehydrogenase DHFR DGAT Dopamine β-hydroxylase Enolase FAAH Factor Xa Ferroptosis Glucokinase HMG-CoA Reductase IDO KRAS-PDEδ MAO Neuronal Metabolism Oxidative Phosphorylation P450 PDE Phospholipase Procollagen C Proteinase Saccharometabolism SCD SGLT TPH Transferase ALP Carbohydrates Transaminase Catalase monooxygenase aldehyde dehydrogenase Squalene synthase Hydrolase ornithine decarboxylase phosphatases Pyruvate kinase MGL Galactosidase 12-Lipoxygenase Fatty Acid Synthase (FASN) Dihydroorotate Dehydrogenase Bone Growth & Remodeling Carbohydrate Metabolism Cofactors & Vitamins Dyslipidemias Metabolic Syndrome Necroptosis Necrosis Nutrient Sensing Phosphodiesterase Reproductive Biology Prolyl Hydroxylation Enzymes Fat Mass and Obesity-associated Protein (FTO) ERK MEK1/2 NKCC MNK PKA p38 Rac Raf JNK cAMP Protein Kinase G RSK Other MAPKAPK MKK KLF MAP3K MAP4K MAPKAPK2 (MK2) Mixed Lineage Kinase Bcr-Abl IGFBR Ack1 Axl ALK BMX Kinase Broad Spectrum Protein Kinase Inhibitor c-FMS c-Kit c-MET CSF-1R DDR1/DDR2 Receptor EGFR EphB4 FAK FGFR FLT3 HER2 IGF1R Insulin Receptor IRAK ITK Lck LRRK2 PDGFR PTKs/RTKs Pyk2 ROR Spleen Tyrosine Kinase (Syk) Src Tie-2 Trk VEGFR Discoidin Domain Receptor DYRK Ephrin Receptor ROS RET TAM Receptor MTH1 ATM/ATR DNA Ligases DNA-PK Nucleoside Antimetabolite/Analogue Telomerase Topoisomerase tankyrase Antifolate CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) IRE1 LIM Kinase (LIMK) TOPK Casein Kinase DNA Intercalating Agents DNA/RNA Oxidative Damage Akt AMPK CK2 GSK-3 MELK mTOR PI3K PI4K PDK-1 PIKfyve PKB S6 Kinase Antibiotic CCR5 CMV gp120/CD4 HBV HCV HIV HSV Influenza virus NA Reverse Transcriptase RSV SRPK SARS-CoV Arenavirus Bacterial Enterovirus Fungal Parasite Virus Protease Coronaviruses MERS COVID-19 Antiviral Cdc42 Cdc7 Chk c-Myc CRM1 Cyclin-Dependent Kinases E1 enzyme G-quadruplex Haspin HMTase Kinesin Ksp Microtubule/Tubulin Mps1 Mitotic RAD51 ROCK Rho PERK PLK PTEN Wee1 PAK Arp2/3 Complex Dynamin ECM & Adhesion Molecules Endomembrane System & Vesicular Trafficking G1 G2/M G2/S Proteolysis Cytoskeleton & Motor Proteins Autophagy DUB E1 Activating E2 conjugating E3 Ligase Proteasome p97 Mitophagy ULK STAT PKC SMAD TGF-βR1(ALK5) TAK1 TGF-β Receptor Antiangiogenics BTK Integrin PAR1 P-selectin Neuropeptide FF/AF Receptors GPCR protein Formyl Peptide Receptors 5-HT Receptor Acetylcholine Adenosine Receptor Adenosine Kinase Adrenergic Receptor Adrenergic Transporters Apelin Receptor Angiotensin Receptor Cannabinoid Receptor CaSR CCR CXCR ETA Receptors Free Fatty Acid Receptors GIP Receptor Glucagon Receptor GLUT1 GPR109A GPR35 Leukotriene Receptor LPL Receptor mGluR Melanocortin (MC) Receptors Non-selective CRF Neurotensin Receptors P2Y Receptor Peptide Receptors Prostaglandin Receptor Prostanoid Receptors Protease-Activated Receptors S1P receptor Somatostatin Receptor Sigma Receptor 17,20-lyase Ras S1P receptor inhibitor Kisspeptin Receptor RGS Protein Cholecystokinin Receptor mAChR Neurokinin Receptor cGMP GRK CK1 EZH2 HSC iPSC Hedgehog Notch Smoothened Wnt/β-catenin Hippo Signaling Cancer stem cell MST1/2 Porcupine YAP AMPAR Piezo Channels ATPase Calcium Channel Cannabinoid Transporters CFTR Chloride Channels GABA Receptor Glucose Transporters Glutamate (EAAT) Transporters Glycine Receptors GlyT GTPase MCT2 Monoamine transporter Monocarboxylate Transporters Multidrug Transporters Na+/Ca2+ Exchanger NMDA Receptor Nucleoside Transporters Pannexin-1 P2X purinergic receptor P-gp Proton Pump Potassium Channel Sodium Channel TRP Channel TRPV1 URAT1 Other Channel Modulators MCT Kainate Receptors sodium-hydrogen exchanger Chloride Channel CRAC Channel EAAT2 HCN Channel Na+/K+ ATPase P-glycoprotein iGluR nAChR VDAC GlyR Cancer Biology Peptides Ras-like GTPases Leukemia Others Tumor Microenvironment Cell Migration & Metastasis Androgen Receptor Aromatase Estrogen/progestogen Receptor GnRH Opioid Receptor RAAS Thyroid hormone Receptor ROR/RAR/RXR FXR & LXR Glucocorticoids & Mineralocorticoids AChR AChE Alzheimer Amyloid β BACE CGRP COX DAPK Dopamine Receptor Gap Junction GluR Histamine Histamine Receptor mPEGS-1 Neuroscience Peptides Nicotinic Receptor P2 Receptor SSRIs Substance P/NK1 Receptor Beta-secretase CaMK Dopamine Transporter Monoamine Oxidase Serotonin Transporter Behavioral Neuroscience Huntington Neuroprotection Ophthalmology Pain Research Parkinson Seizure Disorders Cholinesterases Diabetes NAFLD & NASH Obesity Peptide Inhibitors and Substrate Other Signal Transduction Apoptosis Cyclic GMP-AMP Synthase TLR Papain PGDS PGE synthase SIKs IκB/IKK AP-1 NOD1 NF-κB Interleukin Related 15-lipoxygenase Aryl Hydrocarbon Receptor CD73 Complement System Galectin IFNAR NO Synthase NOD-like Receptor (NLR) STING Reactive Oxygen Species eNOS iNOS nNOS Glutathione Adaptive Immunity Allergy Arthritis Autoimmunity Gastric Disease Immunosuppressants Immunotherapeutics Innate Immunity Pulmonary Diseases Reactive Nitrogen Species Reactive Sulfur Species Acute Phase Reactants Angina Arrhythmia Atherosclerosis Chronic Kidney Disease Coagulation & Hemostasis Coronary Artery Disease Diabetic Nephropathy Endothelium Erythrocytes & Hemoglobin Heart Failure Hypertension Hypotension Lipoproteins Myocardial Contractility Myocardial Hypertrophy Myocardial Infarction Smooth Muscle Cells Stroke Thrombosis Vasoconstriction Vasodilation Cholesterol Metabolism VD/VDR E3 Ligase Ligand-Linker Conjugate PROTAC and Building Blocks Ligand for Target Protein for PROTAC Ligand for E3 Ligase PROTAC SNIPER Antioxidants Lipid Peroxidation Pro-Oxidant Activity Protein Oxidation Actin Inhibitory Antibodies Adenylate cyclase Aldose reductase Arginase Autotaxin ATP citrate lyase BCRP Calmodulin protein kinase II CaM kinase II Ceramidases CERK Collagen proline hydroxylase COMT Cytokine DHODH Diacylglycerol Kinase eIF2a Endopeptidase ES-FLI1/RHA Farnesyl Diphosphate Synthase FBPase FLAP GLI Glycoprotein Glycosylase Saccharides and Glycosides Glyoxalase I GSNOR Guanylate Cyclase Guanylyl Cyclase Gutathione S-transferase Heme oxygenase Hexokinase Hydroxylases IMPDH Inositol Phosphatases Lp-PLA2 LpxC Matrix Metalloprotease MDR multidrug resistance Menin-MLL MGMT Mineralocorticoid Receptor Miscellaneous Compounds MyD88 Myosin NAE NADPH Oxidase Nampt Nitric Oxide Nuclear Receptors Oxygenases/Oxidases PDHK PGC-1α Pregnane X Receptors Reductases Renin Squalene epoxidase SGK sFRP-1 SPHK Synthases/Synthetases Thymidine phosphorylase Transcription Factors β-Lactamase XAO BMI-1 SOD FAS calmodulin Protein synthesis Epac MAGL exocytosis peroxiredoxins Glucosidase Estrogen Receptor/ERR Environmental Toxicology Glycerolipid Lipases Lipases Multidrug-Resistance Proteins Negative Controls Nucleic Acid Turnover/Signaling Organ- & System-Specific Toxicity Pesticides Tec UDP Glucuronosyltransferases Antiprotozoals Microcystins Mycotoxins Peptide Coupling Reagents Amino Acids and Derivatives Unusual Amino Acids Other Reagents Natural Products Phosphatase Inhibitor Cocktails Protease Inhibitor Cocktails Other Inhibitors Cyanine Dyes Enzyme Substrates Fluorescence Biochemical Assay Reagents Deuterium Acyl-CoAs Cyclooxygenase Endocannabinoid/Endocannabinoid-like Fatty Acids Glycerolipids Glycerophospholipids Hydroxy/Hydroperoxy/Epoxy/Oxo Eicosanoids Isoprostanes Leukotrienes Other Lipid Kinases Polyketides Prenol Lipids Prostaglandins Protein Lipidation Reactive O2/N2 Pathways Sphingolipids Sterol Lipids Amyloid β protein 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